1 Executive Summary
2 Preface
2.1 Abstract
2.2 Stake Holders
2.3 Research Scope
2.4 Research Methodology
2.4.1 Data Mining
2.4.2 Data Analysis
2.4.3 Data Validation
2.4.4 Research Approach
2.5 Research Sources
2.5.1 Primary Research Sources
2.5.2 Secondary Research Sources
2.5.3 Assumptions
3 Market Trend Analysis
3.1 Introduction
3.2 Drivers
3.3 Restraints
3.4 Opportunities
3.5 Threats
3.6 Application Analysis
3.7 End User Analysis
3.8 Emerging Markets
3.9 Impact of Covid-19
4 Porters Five Force Analysis
4.1 Bargaining power of suppliers
4.2 Bargaining power of buyers
4.3 Threat of substitutes
4.4 Threat of new entrants
4.5 Competitive rivalry
5 Global In Silico Clinical Trials Market, By Therapeutic Area
5.1 Introduction
5.2 Oncology
5.3 Cardiology
5.4 Diabetes
5.5 Infectious Disease
5.6 Neurology
5.7 Hematology
5.8 Dermatology
5.9 Other Therapeutic Areas
6 Global In Silico Clinical Trials Market, By Phase
6.1 Introduction
6.2 Phase I
6.3 Phase II
6.4 Phase III
6.5 Phase IV
7 Global In Silico Clinical Trials Market, By Application
7.1 Introduction
7.2 Drug Development
7.3 Treatment Optimization
7.4 Medical Devices
7.5 Regulatory Approval
8 Global In Silico Clinical Trials Market, By End User
8.1 Introduction
8.2 Pharmaceutical and Biotechnology Companies
8.3 Contract Research Organizations
8.4 Academic and Research Institutes
8.5 Other End Users
9 Global In Silico Clinical Trials Market, By Geography
9.1 Introduction
9.2 North America
9.2.1 US
9.2.2 Canada
9.2.3 Mexico
9.3 Europe
9.3.1 Germany
9.3.2 UK
9.3.3 Italy
9.3.4 France
9.3.5 Spain
9.3.6 Rest of Europe
9.4 Asia Pacific
9.4.1 Japan
9.4.2 China
9.4.3 India
9.4.4 Australia
9.4.5 New Zealand
9.4.6 South Korea
9.4.7 Rest of Asia Pacific
9.5 South America
9.5.1 Argentina
9.5.2 Brazil
9.5.3 Chile
9.5.4 Rest of South America
9.6 Middle East & Africa
9.6.1 Saudi Arabia
9.6.2 UAE
9.6.3 Qatar
9.6.4 South Africa
9.6.5 Rest of Middle East & Africa
10 Key Developments
10.1 Agreements, Partnerships, Collaborations and Joint Ventures
10.2 Acquisitions & Mergers
10.3 New Product Launch
10.4 Expansions
10.5 Other Key Strategies
11 Company Profiling
11.1 Certara, Inc.
11.2 Insilico Medicine, Inc.
11.3 Novadiscovery Sas
11.4 Dassault Systemes SE
11.5 The AnyLogic Company
11.6 GNS Healthcare Inc.
11.7 InSilicoTrials
11.8 Nuventra Pharma Sciences
11.9 Immunetrics Inc.
11.10 Abzena Ltd.
11.11 Clarivate
11.12 Evotec
11.13 Aitia
11.14 Allucent
11.15 Acellera Ltd.
List of Tables
Table 1 Global In Silico Clinical Trials Market Outlook, By Region (2021-2030) ($MN)
Table 2 Global In Silico Clinical Trials Market Outlook, By Therapeutic Area (2021-2030) ($MN)
Table 3 Global In Silico Clinical Trials Market Outlook, By Oncology (2021-2030) ($MN)
Table 4 Global In Silico Clinical Trials Market Outlook, By Cardiology (2021-2030) ($MN)
Table 5 Global In Silico Clinical Trials Market Outlook, By Diabetes (2021-2030) ($MN)
Table 6 Global In Silico Clinical Trials Market Outlook, By Infectious Disease (2021-2030) ($MN)
Table 7 Global In Silico Clinical Trials Market Outlook, By Neurology (2021-2030) ($MN)
Table 8 Global In Silico Clinical Trials Market Outlook, By Hematology (2021-2030) ($MN)
Table 9 Global In Silico Clinical Trials Market Outlook, By Dermatology (2021-2030) ($MN)
Table 10 Global In Silico Clinical Trials Market Outlook, By Other Therapeutic Areas (2021-2030) ($MN)
Table 11 Global In Silico Clinical Trials Market Outlook, By Phase (2021-2030) ($MN)
Table 12 Global In Silico Clinical Trials Market Outlook, By Phase I (2021-2030) ($MN)
Table 13 Global In Silico Clinical Trials Market Outlook, By Phase II (2021-2030) ($MN)
Table 14 Global In Silico Clinical Trials Market Outlook, By Phase III (2021-2030) ($MN)
Table 15 Global In Silico Clinical Trials Market Outlook, By Phase IV (2021-2030) ($MN)
Table 16 Global In Silico Clinical Trials Market Outlook, By Application (2021-2030) ($MN)
Table 17 Global In Silico Clinical Trials Market Outlook, By Drug Development (2021-2030) ($MN)
Table 18 Global In Silico Clinical Trials Market Outlook, By Treatment Optimization (2021-2030) ($MN)
Table 19 Global In Silico Clinical Trials Market Outlook, By Medical Devices (2021-2030) ($MN)
Table 20 Global In Silico Clinical Trials Market Outlook, By Regulatory Approval (2021-2030) ($MN)
Table 21 Global In Silico Clinical Trials Market Outlook, By End User (2021-2030) ($MN)
Table 22 Global In Silico Clinical Trials Market Outlook, By Pharmaceutical and Biotechnology Companies (2021-2030) ($MN)
Table 23 Global In Silico Clinical Trials Market Outlook, By Contract Research Organizations (2021-2030) ($MN)
Table 24 Global In Silico Clinical Trials Market Outlook, By Academic and Research Institutes (2021-2030) ($MN)
Table 25 Global In Silico Clinical Trials Market Outlook, By Other End Users (2021-2030) ($MN)
Table 26 North America In Silico Clinical Trials Market Outlook, By Country (2021-2030) ($MN)
Table 27 North America In Silico Clinical Trials Market Outlook, By Therapeutic Area (2021-2030) ($MN)
Table 28 North America In Silico Clinical Trials Market Outlook, By Oncology (2021-2030) ($MN)
Table 29 North America In Silico Clinical Trials Market Outlook, By Cardiology (2021-2030) ($MN)
Table 30 North America In Silico Clinical Trials Market Outlook, By Diabetes (2021-2030) ($MN)
Table 31 North America In Silico Clinical Trials Market Outlook, By Infectious Disease (2021-2030) ($MN)
Table 32 North America In Silico Clinical Trials Market Outlook, By Neurology (2021-2030) ($MN)
Table 33 North America In Silico Clinical Trials Market Outlook, By Hematology (2021-2030) ($MN)
Table 34 North America In Silico Clinical Trials Market Outlook, By Dermatology (2021-2030) ($MN)
Table 35 North America In Silico Clinical Trials Market Outlook, By Other Therapeutic Areas (2021-2030) ($MN)
Table 36 North America In Silico Clinical Trials Market Outlook, By Phase (2021-2030) ($MN)
Table 37 North America In Silico Clinical Trials Market Outlook, By Phase I (2021-2030) ($MN)
Table 38 North America In Silico Clinical Trials Market Outlook, By Phase II (2021-2030) ($MN)
Table 39 North America In Silico Clinical Trials Market Outlook, By Phase III (2021-2030) ($MN)
Table 40 North America In Silico Clinical Trials Market Outlook, By Phase IV (2021-2030) ($MN)
Table 41 North America In Silico Clinical Trials Market Outlook, By Application (2021-2030) ($MN)
Table 42 North America In Silico Clinical Trials Market Outlook, By Drug Development (2021-2030) ($MN)
Table 43 North America In Silico Clinical Trials Market Outlook, By Treatment Optimization (2021-2030) ($MN)
Table 44 North America In Silico Clinical Trials Market Outlook, By Medical Devices (2021-2030) ($MN)
Table 45 North America In Silico Clinical Trials Market Outlook, By Regulatory Approval (2021-2030) ($MN)
Table 46 North America In Silico Clinical Trials Market Outlook, By End User (2021-2030) ($MN)
Table 47 North America In Silico Clinical Trials Market Outlook, By Pharmaceutical and Biotechnology Companies (2021-2030) ($MN)
Table 48 North America In Silico Clinical Trials Market Outlook, By Contract Research Organizations (2021-2030) ($MN)
Table 49 North America In Silico Clinical Trials Market Outlook, By Academic and Research Institutes (2021-2030) ($MN)
Table 50 North America In Silico Clinical Trials Market Outlook, By Other End Users (2021-2030) ($MN)
Table 51 Europe In Silico Clinical Trials Market Outlook, By Country (2021-2030) ($MN)
Table 52 Europe In Silico Clinical Trials Market Outlook, By Therapeutic Area (2021-2030) ($MN)
Table 53 Europe In Silico Clinical Trials Market Outlook, By Oncology (2021-2030) ($MN)
Table 54 Europe In Silico Clinical Trials Market Outlook, By Cardiology (2021-2030) ($MN)
Table 55 Europe In Silico Clinical Trials Market Outlook, By Diabetes (2021-2030) ($MN)
Table 56 Europe In Silico Clinical Trials Market Outlook, By Infectious Disease (2021-2030) ($MN)
Table 57 Europe In Silico Clinical Trials Market Outlook, By Neurology (2021-2030) ($MN)
Table 58 Europe In Silico Clinical Trials Market Outlook, By Hematology (2021-2030) ($MN)
Table 59 Europe In Silico Clinical Trials Market Outlook, By Dermatology (2021-2030) ($MN)
Table 60 Europe In Silico Clinical Trials Market Outlook, By Other Therapeutic Areas (2021-2030) ($MN)
Table 61 Europe In Silico Clinical Trials Market Outlook, By Phase (2021-2030) ($MN)
Table 62 Europe In Silico Clinical Trials Market Outlook, By Phase I (2021-2030) ($MN)
Table 63 Europe In Silico Clinical Trials Market Outlook, By Phase II (2021-2030) ($MN)
Table 64 Europe In Silico Clinical Trials Market Outlook, By Phase III (2021-2030) ($MN)
Table 65 Europe In Silico Clinical Trials Market Outlook, By Phase IV (2021-2030) ($MN)
Table 66 Europe In Silico Clinical Trials Market Outlook, By Application (2021-2030) ($MN)
Table 67 Europe In Silico Clinical Trials Market Outlook, By Drug Development (2021-2030) ($MN)
Table 68 Europe In Silico Clinical Trials Market Outlook, By Treatment Optimization (2021-2030) ($MN)
Table 69 Europe In Silico Clinical Trials Market Outlook, By Medical Devices (2021-2030) ($MN)
Table 70 Europe In Silico Clinical Trials Market Outlook, By Regulatory Approval (2021-2030) ($MN)
Table 71 Europe In Silico Clinical Trials Market Outlook, By End User (2021-2030) ($MN)
Table 72 Europe In Silico Clinical Trials Market Outlook, By Pharmaceutical and Biotechnology Companies (2021-2030) ($MN)
Table 73 Europe In Silico Clinical Trials Market Outlook, By Contract Research Organizations (2021-2030) ($MN)
Table 74 Europe In Silico Clinical Trials Market Outlook, By Academic and Research Institutes (2021-2030) ($MN)
Table 75 Europe In Silico Clinical Trials Market Outlook, By Other End Users (2021-2030) ($MN)
Table 76 Asia Pacific In Silico Clinical Trials Market Outlook, By Country (2021-2030) ($MN)
Table 77 Asia Pacific In Silico Clinical Trials Market Outlook, By Therapeutic Area (2021-2030) ($MN)
Table 78 Asia Pacific In Silico Clinical Trials Market Outlook, By Oncology (2021-2030) ($MN)
Table 79 Asia Pacific In Silico Clinical Trials Market Outlook, By Cardiology (2021-2030) ($MN)
Table 80 Asia Pacific In Silico Clinical Trials Market Outlook, By Diabetes (2021-2030) ($MN)
Table 81 Asia Pacific In Silico Clinical Trials Market Outlook, By Infectious Disease (2021-2030) ($MN)
Table 82 Asia Pacific In Silico Clinical Trials Market Outlook, By Neurology (2021-2030) ($MN)
Table 83 Asia Pacific In Silico Clinical Trials Market Outlook, By Hematology (2021-2030) ($MN)
Table 84 Asia Pacific In Silico Clinical Trials Market Outlook, By Dermatology (2021-2030) ($MN)
Table 85 Asia Pacific In Silico Clinical Trials Market Outlook, By Other Therapeutic Areas (2021-2030) ($MN)
Table 86 Asia Pacific In Silico Clinical Trials Market Outlook, By Phase (2021-2030) ($MN)
Table 87 Asia Pacific In Silico Clinical Trials Market Outlook, By Phase I (2021-2030) ($MN)
Table 88 Asia Pacific In Silico Clinical Trials Market Outlook, By Phase II (2021-2030) ($MN)
Table 89 Asia Pacific In Silico Clinical Trials Market Outlook, By Phase III (2021-2030) ($MN)
Table 90 Asia Pacific In Silico Clinical Trials Market Outlook, By Phase IV (2021-2030) ($MN)
Table 91 Asia Pacific In Silico Clinical Trials Market Outlook, By Application (2021-2030) ($MN)
Table 92 Asia Pacific In Silico Clinical Trials Market Outlook, By Drug Development (2021-2030) ($MN)
Table 93 Asia Pacific In Silico Clinical Trials Market Outlook, By Treatment Optimization (2021-2030) ($MN)
Table 94 Asia Pacific In Silico Clinical Trials Market Outlook, By Medical Devices (2021-2030) ($MN)
Table 95 Asia Pacific In Silico Clinical Trials Market Outlook, By Regulatory Approval (2021-2030) ($MN)
Table 96 Asia Pacific In Silico Clinical Trials Market Outlook, By End User (2021-2030) ($MN)
Table 97 Asia Pacific In Silico Clinical Trials Market Outlook, By Pharmaceutical and Biotechnology Companies (2021-2030) ($MN)
Table 98 Asia Pacific In Silico Clinical Trials Market Outlook, By Contract Research Organizations (2021-2030) ($MN)
Table 99 Asia Pacific In Silico Clinical Trials Market Outlook, By Academic and Research Institutes (2021-2030) ($MN)
Table 100 Asia Pacific In Silico Clinical Trials Market Outlook, By Other End Users (2021-2030) ($MN)
Table 101 South America In Silico Clinical Trials Market Outlook, By Country (2021-2030) ($MN)
Table 102 South America In Silico Clinical Trials Market Outlook, By Therapeutic Area (2021-2030) ($MN)
Table 103 South America In Silico Clinical Trials Market Outlook, By Oncology (2021-2030) ($MN)
Table 104 South America In Silico Clinical Trials Market Outlook, By Cardiology (2021-2030) ($MN)
Table 105 South America In Silico Clinical Trials Market Outlook, By Diabetes (2021-2030) ($MN)
Table 106 South America In Silico Clinical Trials Market Outlook, By Infectious Disease (2021-2030) ($MN)
Table 107 South America In Silico Clinical Trials Market Outlook, By Neurology (2021-2030) ($MN)
Table 108 South America In Silico Clinical Trials Market Outlook, By Hematology (2021-2030) ($MN)
Table 109 South America In Silico Clinical Trials Market Outlook, By Dermatology (2021-2030) ($MN)
Table 110 South America In Silico Clinical Trials Market Outlook, By Other Therapeutic Areas (2021-2030) ($MN)
Table 111 South America In Silico Clinical Trials Market Outlook, By Phase (2021-2030) ($MN)
Table 112 South America In Silico Clinical Trials Market Outlook, By Phase I (2021-2030) ($MN)
Table 113 South America In Silico Clinical Trials Market Outlook, By Phase II (2021-2030) ($MN)
Table 114 South America In Silico Clinical Trials Market Outlook, By Phase III (2021-2030) ($MN)
Table 115 South America In Silico Clinical Trials Market Outlook, By Phase IV (2021-2030) ($MN)
Table 116 South America In Silico Clinical Trials Market Outlook, By Application (2021-2030) ($MN)
Table 117 South America In Silico Clinical Trials Market Outlook, By Drug Development (2021-2030) ($MN)
Table 118 South America In Silico Clinical Trials Market Outlook, By Treatment Optimization (2021-2030) ($MN)
Table 119 South America In Silico Clinical Trials Market Outlook, By Medical Devices (2021-2030) ($MN)
Table 120 South America In Silico Clinical Trials Market Outlook, By Regulatory Approval (2021-2030) ($MN)
Table 121 South America In Silico Clinical Trials Market Outlook, By End User (2021-2030) ($MN)
Table 122 South America In Silico Clinical Trials Market Outlook, By Pharmaceutical and Biotechnology Companies (2021-2030) ($MN)
Table 123 South America In Silico Clinical Trials Market Outlook, By Contract Research Organizations (2021-2030) ($MN)
Table 124 South America In Silico Clinical Trials Market Outlook, By Academic and Research Institutes (2021-2030) ($MN)
Table 125 South America In Silico Clinical Trials Market Outlook, By Other End Users (2021-2030) ($MN)
Table 126 Middle East & Africa In Silico Clinical Trials Market Outlook, By Country (2021-2030) ($MN)
Table 127 Middle East & Africa In Silico Clinical Trials Market Outlook, By Therapeutic Area (2021-2030) ($MN)
Table 128 Middle East & Africa In Silico Clinical Trials Market Outlook, By Oncology (2021-2030) ($MN)
Table 129 Middle East & Africa In Silico Clinical Trials Market Outlook, By Cardiology (2021-2030) ($MN)
Table 130 Middle East & Africa In Silico Clinical Trials Market Outlook, By Diabetes (2021-2030) ($MN)
Table 131 Middle East & Africa In Silico Clinical Trials Market Outlook, By Infectious Disease (2021-2030) ($MN)
Table 132 Middle East & Africa In Silico Clinical Trials Market Outlook, By Neurology (2021-2030) ($MN)
Table 133 Middle East & Africa In Silico Clinical Trials Market Outlook, By Hematology (2021-2030) ($MN)
Table 134 Middle East & Africa In Silico Clinical Trials Market Outlook, By Dermatology (2021-2030) ($MN)
Table 135 Middle East & Africa In Silico Clinical Trials Market Outlook, By Other Therapeutic Areas (2021-2030) ($MN)
Table 136 Middle East & Africa In Silico Clinical Trials Market Outlook, By Phase (2021-2030) ($MN)
Table 137 Middle East & Africa In Silico Clinical Trials Market Outlook, By Phase I (2021-2030) ($MN)
Table 138 Middle East & Africa In Silico Clinical Trials Market Outlook, By Phase II (2021-2030) ($MN)
Table 139 Middle East & Africa In Silico Clinical Trials Market Outlook, By Phase III (2021-2030) ($MN)
Table 140 Middle East & Africa In Silico Clinical Trials Market Outlook, By Phase IV (2021-2030) ($MN)
Table 141 Middle East & Africa In Silico Clinical Trials Market Outlook, By Application (2021-2030) ($MN)
Table 142 Middle East & Africa In Silico Clinical Trials Market Outlook, By Drug Development (2021-2030) ($MN)
Table 143 Middle East & Africa In Silico Clinical Trials Market Outlook, By Treatment Optimization (2021-2030) ($MN)
Table 144 Middle East & Africa In Silico Clinical Trials Market Outlook, By Medical Devices (2021-2030) ($MN)
Table 145 Middle East & Africa In Silico Clinical Trials Market Outlook, By Regulatory Approval (2021-2030) ($MN)
Table 146 Middle East & Africa In Silico Clinical Trials Market Outlook, By End User (2021-2030) ($MN)
Table 147 Middle East & Africa In Silico Clinical Trials Market Outlook, By Pharmaceutical and Biotechnology Companies (2021-2030) ($MN)
Table 148 Middle East & Africa In Silico Clinical Trials Market Outlook, By Contract Research Organizations (2021-2030) ($MN)
Table 149 Middle East & Africa In Silico Clinical Trials Market Outlook, By Academic and Research Institutes (2021-2030) ($MN)
Table 150 Middle East & Africa In Silico Clinical Trials Market Outlook, By Other End Users (2021-2030) ($MN)
| ※参考情報 インシリコ臨床試験とは、コンピュータモデルやシミュレーション技術を用いて行う臨床試験のことを指します。この手法は、実際の臨床試験に代わるものではなく、あくまで補完的な役割を担います。インシリコ臨床試験を通じて、薬剤の効果や安全性、治療の結果を予測することで、実際の試験が行われる前に有用なデータを得ることができます。 インシリコ臨床試験には、いくつかの種類があります。第一のタイプは、ドメイン知識に基づいたモデル化です。ここでは、既存の生物学的知見をもとに、薬剤や治療法の作用機序を理解するための定量的モデルを構築します。第二のタイプは、機械学習やデータマイニングを活用したアプローチです。膨大な量の健康データや遺伝情報を解析し、特定の疾患に対する治療の効果を予測します。第三のタイプは、シミュレーションによる予測の実施です。特定の患者群を模した仮想環境を構築し、薬剤の投与や患者の反応をシミュレーションします。 インシリコ臨床試験の用途は多岐にわたります。まず、新薬開発の初期段階において、候補薬のスクリーニングや最適化を行うために使用されます。薬剤の効果や副作用を予測することで、より効率的に次のステップである臨床試験に進むことが可能になります。また、患者選択や治療戦略の最適化にも役立ちます。異なる患者群に対して治療効果がどう異なるかを予測することで、個別化医療の実現に寄与します。 さらに、インシリコ臨床試験は、特定の疾患に対する新しい治療法の開発や、既存の治療法の改善にも役立ちます。例えば、がん治療においては、腫瘍の成長や転移のパターンをモデル化し、最適な治療法を探索することができます。また、新型コロナウイルス感染症（COVID-19）に関する研究でも、この手法が重要な役割を果たしました。ウイルスの挙動やワクチンの効果をシミュレーションすることで、迅速な対策が立案されました。 関連技術としては、人工知能（AI）や機械学習、ビッグデータ解析、システム生物学、バイオインフォマティクスなどが挙げられます。これらの技術は、膨大なデータを処理し、複雑な生物システムを理解するための基盤を提供します。AIを利用することで、非線形な関係や潜在的なパターンを発見することが容易になり、より精密な予測が可能となります。 さらに、バーチャルリアリティ（VR）や拡張現実（AR）の技術も、インシリコ臨床試験の分野で活用されています。特に、医療教育や患者の理解を深めるために、インタラクティブなシミュレーションが作られています。これにより、医療者や患者が治療法の選択肢を視覚的に体験でき、理解が促進されます。 インシリコ臨床試験は、薬剤開発や治療方法の最適化において重要な役割を果たしているものの、実際の臨床試験を完全に置き換えることはできません。実際の患者における多様な要因や副作用を観察することは、現実の臨床研究においてしか得られない貴重な情報です。そのため、インシリコ試験が出した結果を裏付けるためには、従来の臨床試験が引き続き必要です。 今後、インシリコ臨床試験はますます普及し、医学や製薬業界において革新的な合成モデルやシステムが登場することでしょう。データ駆動型医療の進展により、個々の患者に最適化された治療法の提供が実現することが期待されています。技術の進化とともに、インシリコ臨床試験がもたらす新たな可能性に注目が集まっています。 |
