タンパク発現の世界市場予測(~2022年):大腸菌、哺乳類、イースト、ピキア属、昆虫、バキュロウイルス、無細胞

◆英語タイトル:Protein Expression Market by Type (E. Coli, Mammalian, Yeast, Pichia, Insect, Baculovirus, Cell-free), Products (Competent Cells, Reagents, Instruments, Services), Application (Therapeutic, Research, Industrial) & End User - Global Forecast to 2022
◆商品コード:MAM-BT2435
◆発行会社(調査会社):MarketsandMarkets
◆発行日:2017年7月4日
◆ページ数:176
◆レポート言語:英語
◆レポート形式:PDF
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◆産業分野:バイオ技術
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【レポートの概要】

Protein expression is a technique or methodology in which proteins are characterized, modified, and synthesized in the host cells. The selected protein is typically achieved by the modification or alteration of the protein expression process in a living cell. Various kinds of protein expression systems are used for the production of a broad range of therapeutic proteins such as insulin, interferons, and interleukins. The global market is expected to reach USD 2.850.5 Million by 2022 from USD 1,654.0 Million in 2017, at a CAGR of 11.5% during the forecast period. The rising prevalence of chronic disorders disease, the growing number of life sciences and biopharmaceutical industries, rising research activities on recombinant-based protein expression and technological advancements in protein expression systems are the major driving factors for this market.
The protein expression systems market is segmented on the basis of systems type, product, application and end user. On the basis of systems type, the market is segmented into insect cell expression systems; mammalian cell expression systems; prokaryotic expression systems, yeast expression systems; cell-free expression systems; and algal-based expression systems. The prokaryotic expression systems segment is expected to account for the largest share of the market in 2017. The growth in this segment is primarily attributed to the frequent use of prokaryotic protein expression systems as they are cheaper compared to other expression systems.

On the basis of product, the market is segmented into competent cells, expression vectors, instruments, reagents, and services. The reagents segment is expected to hold the largest market share of the protein expression market. This is primarily due to the increasing protein expression research activities and the large-scale production of antibodies and vaccines.

By application, the protein expression market is segmented into therapeutic applications, research applications and industrial applications. The therapeutic applications segment is expected to account for the largest share of the market in 2017. The growth in this segment is primarily attributed to increasing prevalence of chronic diseases such as cancer and diabetes around the world.

Based on end user, the market has been segmented into academic research institutes; contract research organizations (CROs); pharmaceutical and biotechnology companies; and other end users (food processing industry, detergent manufacturers, paper industry, leather industry, breweries, dairy industry, chemical industry, bioplastic industry, and cosmeceutical industry). The pharmaceutical and biotechnology companies segment is expected to dominate the market during the forecast period, owing to technological advancement in protein expression research and the rising production of recombinant therapeutic proteins for disease treatment.

By region, the market is segmented into North America, Europe, Asia, and the Rest of the World (RoW). The market is dominated by North America, followed by Europe. However, the Asian region is expected to witness the highest growth during the forecast period. The presence of emerging economies like China and India; rising prevalence of chronic diseases are some of the key factors driving the high growth of this regional segment.

The high cost of protein expression instruments & reagents and increasing consolidation in the protein expression are the restraining factors for this market.

Thermo Fisher Scientific Inc. (U.S.), Merck KGaA (Germany), Takara Bio Inc. (Japan), Promega Corporation (U.S.), Genscript Biotech Corporation (China), and Agilent Technologies Inc. (U.S.) are the top six players in this market. These companies have a broad product portfolio with comprehensive features and have a strong geographical presence. Further, these leaders cater to the requirements of major end users such as research laboratories and pharmaceutical & biotechnology companies.

【レポートの目次】

1 Introduction (Page No. – 16)
1.1 Objectives of the Study
1.2 Market Definition
1.3 Market Scope
1.4 Years Considered for the Study
1.5 Currency
1.6 Limitations
1.7 Stakeholders

2 Research Methodology (Page No. – 19)
2.1 Secondary Data
2.2 Primary Data
2.3 Market Size Estimation
2.3.1 Bottom-Up Approach
2.3.2 Top-Down Approach
2.4 Data Triangulation
2.5 Assumptions for the Study

3 Executive Summary (Page No. – 27)

4 Premium Insights (Page No. – 31)
4.1 Market Overview
4.2 Geographic Analysis: By End User (2017)
4.3 Protein Expression Market, By System Type, 2017–2022
4.4 Geographical Snapshot

5 Market Overview (Page No. – 35)
5.1 Introduction
5.2 Market Dynamics
5.2.1 Drivers
5.2.1.1 Increasing Incidence of Chronic Diseases
5.2.1.1.1 Growth in the Geriatric Population
5.2.1.1.2 Increasing Demand for Protein Biologics
5.2.1.2 Growth in Life Sciences and Biopharmaceutical Industries
5.2.1.3 Increasing Research Activities on Recombinant-Based Protein Expression
5.2.1.4 Availability of Funding for Protein-Based Research
5.2.1.5 Technological Advancements in Protein Expression Systems
5.2.2 Restraints
5.2.2.1 High Cost of Protein Expression Reagents and Instruments
5.2.2.2 Increasing Consolidation and High Barriers for New Entrants
5.2.3 Opportunities
5.2.3.1 Emergence of Microfluidics
5.2.3.2 Emerging Economies Offer Ample Growth Potential
5.2.4 Challenges
5.2.4.1 Contamination—A Major Challenge in Protein Purification
5.2.4.2 Complexities Associated With Membrane Protein Expression and Purification

6 Global Protein Expression Market, By System Type (Page No. – 44)
6.1 Introduction
6.2 Prokaryotic Expression Systems
6.2.1 Escherichia Coli Systems
6.2.2 Other Prokaryotic Expression Systems
6.3 Mammalian Cell Expression Systems
6.3.1 Chinese Hamster Ovary Systems
6.3.2 Other Mammalian Cell Systems
6.4 Insect Cell Expression Systems
6.4.1 Baculovirus Systems
6.4.2 Other Insect Cell Systems
6.5 Yeast Expression Systems
6.5.1 K. Lactis Systems
6.5.2 Saccharomyces Systems
6.5.3 Pichia Systems
6.5.4 Other Yeast Expression Systems
6.6 Cell-Free Expression Systems
6.7 Algal-Based Expression Systems

7 Global Protein Expression Market, By Product and Service (Page No. – 61)
7.1 Introduction
7.2 Reagents
7.3 Expression Vectors
7.4 Competent Cells
7.5 Instruments
7.6 Services

8 Global Protein Expression Market, By Application (Page No. – 68)
8.1 Introduction
8.2 Therapeutic Applications
8.3 Industrial Applications
8.4 Research Applications

9 Global Protein Expression Market, By End User (Page No. – 74)
9.1 Introduction
9.2 Pharmaceutical and Biotechnology Companies
9.3 Academic Research Institutes
9.4 Contract Research Organizations
9.5 Other End Users

10 Global Protein Expression Market, By Region (Page No. – 79)
10.1 Introduction
10.2 North America
10.2.1 U.S.
10.2.2 Canada
10.3 Europe
10.3.1 Germany
10.3.2 France
10.3.3 U.K.
10.3.4 Italy
10.3.5 Spain
10.3.6 Rest of Europe (RoE)
10.4 Asia
10.4.1 China
10.4.2 Japan
10.4.3 India
10.4.4 Rest of Asia (RoA)
10.5 Rest of the World (RoW)

11 Competitive Landscape (Page No. – 129)
11.1 Introduction
11.1.1 Visionary Leaders
11.1.2 Innovators
11.1.3 Dynamic Differentiators
11.1.4 Emerging Companies
11.2 Competitive Leadership Mapping
11.2.1 Strength of Product Portfolio (25 Players)
11.2.2 Business Strategy Excellence (25 Players)
*Top 25 Companies Analyzed for This Study are – Merck KGaA (Germany), Thermo Fisher Scientific Inc. (U.S.), Becton, Dickinson & Company (U.S.), Agilent Technologies, Inc. (U.S.), Qiagen N.V. (Netherlands), Takara Bio Inc. (Japan), Lonza Group Ltd. (Switzerland), Bio-Rad Laboratories, Inc. (U.S.), Genscript Biotech Corporation (China), Lucigen Corporation (U.S.), Synthetic Genomics Inc. (U.S.), Promega Corporation (U.S.), New England Biolabs, Inc. (U.S.), Sengenics (Singapore.), Artes Biotechnology GmbH (Germany), Addgene Inc. (U.S.) , Lifesensors Inc. (U.S.), Accelagen Inc. (U.S.), Geneva Biotech (Switzerland), Viva Biotech (China), Profacgen (U.S.), Proteogenix (France), Peak Proteins Ltd. (U.K.), Domainex Ltd. (U.K.), and Jena Bioscience GmbH (Germany).
11.3 Market Share Analysis

12 Company Profiles (Page No. – 135)
12.1 Key Companies
(Overview, Products and Services, Financials, Strategy & Development)*
12.1.1 Thermo Fisher Scientific Inc.
12.1.2 Merck KGaA
12.1.3 Genscript Biotech Corporation
12.1.4 Agilent Technologies, Inc.
12.1.5 Takara Bio Inc.
12.1.6 Promega Corporation
12.1.7 Bio-Rad Laboratories, Inc.
12.1.8 Qiagen N.V.
12.1.9 Lonza Group Ltd.
12.1.10 New England Biolabs Inc.
*Details on Overview, Products and Services, Financials, Strategy & Development Might Not Be Captured in Case of Unlisted Companies.
12.2 Key Innovators
12.2.1 Sengenics
12.2.2 Proteogenix
12.2.3 Synthetic Genomics Inc.

13 Appendix (Page No. – 163)
13.1 Industry Insights
13.2 Discussion Guide
13.3 Knowledge Store: Marketsandmarkets’ Subscription Portal
13.4 Introducing RT: Real-Time Market Intelligence
13.5 Available Customizations
13.6 Related Reports
13.7 Author Details

List of Tables (127 Tables)

Table 1 Protein Expression: Market Snapshot
Table 2 Proteins Synthesized By Protein Expression and Genetic Engineering
Table 3 Projected Increase in Number of Cancer Patients, By Type (2012 vs 2015 vs and 2035)
Table 4 Pharmaceutical Products and Cell Lines Used to Produce Them
Table 5 Government Funding for Protein-Based Research (2013 – 2017)
Table 6 Protein Expression Market, By System Type, 2015–2022 (USD Million)
Table 7 Prokaryotic Expression Systems Market, By Region, 2015–2022 (USD Million)
Table 8 Prokaryotic Expression Systems Market, By Type, 2015–2022 (USD Million)
Table 9 E.Coli Systems Market, By Region, 2015–2022 (USD Million)
Table 10 Other Prokaryotic Expression Systems Market, By Region, 2015–2022 (USD Million)
Table 11 Mammalian Cell Expression Systems Market, By Region, 2015–2022 (USD Million)
Table 12 Mammalian Cell Expression Systems Market, By Type, 2015–2022 (USD Million)
Table 13 Cho Systems Segment Market, By Region, 2015–2022 (USD Million)
Table 14 Other Mammalian Cell Systems Market, By Region, 2015–2022 (USD Million)
Table 15 Insect Cell Expression Systems Market, By Region, 2015–2022 (USD Million)
Table 16 Insect Cell Expression Systems Market, By Type, 2015–2022 (USD Million)
Table 17 Baculovirus Systems Market, By Region, 2015–2022 (USD Million)
Table 18 Other Insect Cell Systems Market, By Region, 2015–2022 (USD Million)
Table 19 Yeast Expression Systems Market, By Region, 2015–2022 (USD Million)
Table 20 Yeast Expression Systems Market, By Type, 2015–2022 (USD Million)
Table 21 K. Lactis Systems Market, By Region, 2015–2022 (USD Million)
Table 22 Saccharomyces Systems Market, By Region, 2015–2022 (USD Million)
Table 23 Pichia Systems Market, By Region, 2015–2022 (USD Million)
Table 24 Other Yeast Systems Market, By Region, 2015–2022 (USD Million)
Table 25 Cell-Free Expression Systems Market, By Region, 2015–2022 (USD Million)
Table 26 Algal-Based Expression Systems Market, By Region, 2015–2022 (USD Million)
Table 27 Protein Expression Market, By Product and Service, 2015–2022 (USD Million)
Table 28 Protein Expression Reagents Market, By Region, 2015–2022 (USD Million)
Table 29 Protein Expression Vectors Market, By Region, 2015–2022 (USD Million)
Table 30 Protein Expression Competent Cells Market, By Region, 2015–2022 (USD Million)
Table 31 Protein Expression Instruments Market, By Region, 2015–2022 (USD Million)
Table 32 Protein Expression Services Market, By Region, 2015–2022 (USD Million)
Table 33 Protein Expression Market, By Application, 2015–2022 (USD Million)
Table 34 Therapeutic Proteins & Their Applications
Table 35 Therapeutic Applications Market, By Region, 2015–2022 (USD Million)
Table 36 Industrial Applications Market, By Region, 2015–2022 (USD Million)
Table 37 Research Applications Market, By Region, 2015–2022 (USD Million)
Table 38 Protein Expression Market, By End User, 2015–2022 (USD Million)
Table 39 Pharmaceutical and Biotechnology Companies Market, By Region, 2015–2022 (USD Million)
Table 40 Academic Research Institutes Market, By Region, 2015–2022 (USD Million)
Table 41 Contract Research Organizations Market, By Region, 2015–2022 (USD Million)
Table 42 Other End Users Market, By Region, 2015–2022 (USD Million)
Table 43 Protein Expression Market, By Region, 2015–2022 (USD Million)
Table 44 North America: Protein Expression Market, By Country, 2015–2022 (USD Million)
Table 45 North America: Protein Expression Market, By System Type, 2015–2022 (USD Million)
Table 46 North America: Prokaryotic Expression Systems Market, By Type, 2015–2022 (USD Million)
Table 47 North America: Mammalian Cell Expression Systems Market, By Type, 2015–2022 (USD Million)
Table 48 North America: Insect Cell Expression Systems Market, By Type, 2015–2022 (USD Million)
Table 49 North America: Yeast Expression Systems Market, By Type, 2015–2022 (USD Million)
Table 50 North America: Protein Expression Market, By Product & Service, 2015–2022 (USD Million)
Table 51 North America: Protein Expression Market, By Application, 2015–2022 (USD Million)
Table 52 North America: Protein Expression Market, By End User, 2015–2022 (USD Million)
Table 53 U.S. Biotechnology Market, 2014–2015 (USD Billion)
Table 54 U.S.: Protein Expression Market, By System Type, 2015–2022 (USD Million)
Table 55 U.S.: Market, By Product & Service, 2015–2022 (USD Million)
Table 56 U.S.: Market, By Application, 2015–2022 (USD Million)
Table 57 U.S.: Market, By End User, 2015–2022 (USD Million)
Table 58 Canada: Protein Expression Market, By System Type, 2015–2022 (USD Million)
Table 59 Canada: Market, By Product & Service, 2015–2022 (USD Million)
Table 60 Canada: Market, By Application, 2015–2022 (USD Million)
Table 61 Canada: Protein Expression Market, By End User, 2015–2022 (USD Million)
Table 62 Europe: Market, By Country, 2015–2022 (USD Million)
Table 63 Europe: Protein Expression Market, By System Type, 2015–2022 (USD Million)
Table 64 Europe: Prokaryotic Expression Systems Market, By Type, 2015–2022 (USD Million)
Table 65 Europe: Mammalian Cell Expression Systems Market, By Type, 2015–2022 (USD Million)
Table 66 Europe: Insect Cell Expression Systems Market, By Type, 2015–2022 (USD Million)
Table 67 Europe: Yeast Expression Systems Market, By Type, 2015–2022 (USD Million)
Table 68 Europe: Protein Expression Market, By Product & Service, 2015–2022 (USD Million)
Table 69 Europe: Protein Expression Market, By Application, 2015–2022 (USD Million)
Table 70 Europe: Protein Expression Market, By End User, 2015–2022 (USD Million)
Table 71 Germany: Protein Expression Market, By System Type, 2015–2022 (USD Million)
Table 72 Germany: Market, By Product & Service, 2015–2022 (USD Million)
Table 73 Germany: Protein Expression Market, By Application, 2015–2022 (USD Million)
Table 74 Germany: Protein Expression Market, By End User, 2015–2022 (USD Million)
Table 75 France: Protein Expression Market, By System Type, 2015–2022 (USD Million)
Table 76 France: Market, By Product & Service, 2015–2022 (USD Million)
Table 77 France: Market, By Application, 2015–2022 (USD Million)
Table 78 France: Protein Expression Market, By End User, 2015–2022 (USD Million)
Table 79 U.K.: Protein Expression Market, By System Type, 2015–2022 (USD Million)
Table 80 U.K.: Market, By Product & Service, 2015–2022 (USD Million)
Table 81 U.K.: Market, By Application, 2015–2022 (USD Million)
Table 82 U.K.: Market, By End User, 2015–2022 (USD Million)
Table 83 Italy: Protein Expression Market, By System Type, 2015–2022 (USD Million)
Table 84 Italy: Market, By Product & Service, 2015–2022 (USD Million)
Table 85 Italy: Market, By Application, 2015–2022 (USD Million)
Table 86 Italy: Protein Expression Market, By End User, 2015–2022 (USD Million)
Table 87 Spain: Protein Expression Market, By System Type, 2015–2022 (USD Million)
Table 88 Spain: Market, By Product & Service, 2015–2022 (USD Million)
Table 89 Spain: Market, By Application, 2015–2022 (USD Million)
Table 90 Spain: Market, By End User, 2015–2022 (USD Million)
Table 91 RoE: Protein Expression Market, By System Type, 2015–2022 (USD Million)
Table 92 RoE: Market, By Product & Service, 2015–2022 (USD Million)
Table 93 RoE: Market, By Application, 2015–2022 (USD Million)
Table 94 RoE: Protein Expression Market, By End User, 2015–2022 (USD Million)
Table 95 Asia: Protein Expression Market, By Country, 2015–2022 (USD Million)
Table 96 Asia: Market, By System Type, 2015–2022 (USD Million)
Table 97 Asia: Prokaryotic Expression Systems Market, By Type, 2015–2022 (USD Million)
Table 98 Asia: Mammalian Cell Expression Systems Market, By Type, 2015–2022 (USD Million)
Table 99 Asia: Insect Cell Expression Systems Market, By Type, 2015–2022 (USD Million)
Table 100 Asia: Yeast Expression Systems Market, By Type, 2015–2022 (USD Million)
Table 101 Asia: Protein Expression Market, By Product & Service, 2015–2022 (USD Million)
Table 102 Asia: Market, By Application, 2015–2022 (USD Million)
Table 103 Asia: Market, By End User, 2015–2022 (USD Million)
Table 104 China: Protein Expression Market, By System Type, 2015–2022 (USD Million)
Table 105 China: Protein Expression Market, By Product & Service, 2015–2022 (USD Million)
Table 106 China: Market, By Application, 2015–2022 (USD Million)
Table 107 China: Market, By End User, 2015–2022 (USD Million)
Table 108 Japan: Protein Expression Market, By System Type, 2015–2022 (USD Million)
Table 109 Japan: Market, By Product & Service, 2015–2022 (USD Million)
Table 110 Japan: Market, By Application, 2015–2022 (USD Million)
Table 111 Japan: Protein Expression Market, By End User, 2015–2022 (USD Million)
Table 112 India: Protein Expression Market, By System Type, 2015–2022 (USD Million)
Table 113 India: Market, By Product & Service, 2015–2022 (USD Million)
Table 114 India: Market, By Application, 2015–2022 (USD Million)
Table 115 India: Market, By End User, 2015–2022 (USD Million)
Table 116 RoA: Protein Expression Market, By System Type, 2015–2022 (USD Million)
Table 117 RoA: Market, By Product & Service, 2015–2022 (USD Million)
Table 118 RoA: Market, By End User, 2015–2022 (USD Million)
Table 119 RoA: Protein Expression Market, By End User, 2015–2022 (USD Million)
Table 120 RoW: Protein Expression Market, By System Type, 2015–2022 (USD Million)
Table 121 RoW: Prokaryotic Expression Systems Market, By Type, 2015–2022 (USD Million)
Table 122 RoW: Mammalian Cell Expression Systems Market, By Type, 2015–2022 (USD Million)
Table 123 RoW: Insect Cell Expression Systems Market, By Type, 2015–2022 (USD Million)
Table 124 RoW: Yeast Expression Systems Market, By Type, 2015–2022 (USD Million)
Table 125 RoW: Protein Expression Market, By Product & Service, 2015–2022 (USD Million)
Table 126 RoW: Protein Expression Market, By Application, 2015–2022 (USD Million)
Table 127 RoW: Market, By End User, 2015–2022 (USD Million)

List of Figures (38 Figures)

Figure 1 Research Design
Figure 2 Key Data From Secondary Sources
Figure 3 Key Data From Primary Sources
Figure 4 Protein Expression Market: Bottom-Up Approach
Figure 5 Top-Down Approach
Figure 6 Data Triangulation Methodology
Figure 7 Protein Expression Market, By System Type, 2017 vs 2022 (USD Billion)
Figure 8 Protein Expression Market, By Product & Service, 2017 vs 2022 (USD Billion)
Figure 9 Protein Expression Market, By Application, 2017 vs 2022 (USD Billion)
Figure 10 Protein Expression Market, By End User, 2017 vs 2022 (USD Billion)
Figure 11 Protein Expression Market, By Region, 2017 vs 2022 (USD Billion)
Figure 12 Growing Prevalence of Chronic Diseases is Driving the Growth of the Protein Expression Market During the Forecast Period
Figure 13 Mammalian Cell Expression Systems Will Register the Highest CAGR During the Forecast Period
Figure 14 Asia to Register the Highest CAGR During the Forecast Period
Figure 15 Drivers, Restraints, Opportunities, and Challenges
Figure 16 Diabetes Cases, 2015 vs 2040 (Million)
Figure 17 Prokaryotic Expression Systems Segment to Dominate the Protein Expression Market During the Forecast Period
Figure 18 North America to Dominate the Prokaryotic Expression Systems Segment During 2017 and 2022
Figure 19 Reagents Segment to Dominate the Protein Expression Market During the Forecast Period
Figure 20 Therapeutic Applications to Dominate the Protein Expression Market During the Forecast Period
Figure 21 North America to Dominate the Therapeutic Applications Market During the Forecast Period
Figure 22 Pharmaceutical and Biotechnology Companies Segment to Dominate the Market During the Forecast Period
Figure 23 Asia to Register the Highest Growth Rate in the Global Market Between 2017 and 2022
Figure 24 North America: Market Snapshot
Figure 25 Prokaryotic Expression Systems to Account for the Largest Share of the U.S. Protein Expression Market in 2017
Figure 26 Europe: Market Snapshot
Figure 27 Asia: Market Snapshot
Figure 28 RoW: Market Snapshot
Figure 29 Market (Global) Competitive Leadership Mapping, 2017
Figure 30 Market Share (2016)
Figure 31 Thermo Fisher Scientific Inc.: Company Snapshot (2016)
Figure 32 Merck KGaA Company Snapshot (2016)
Figure 33 Genscript Biotech Corporation: Company Snapshot (2016)
Figure 34 Agilent Technologies Inc. (U.S.): Company Snapshot (2016)
Figure 35 Takara Bio Inc. Company Snapshot (2016)
Figure 36 Bio-Rad Laboratories, Inc.: Company Snapshot (2016)
Figure 37 Qiagen N.V.: Company Snapshot (2016)
Figure 38 Lonza Group Ltd.: Company Snapshot (2016)

【レポートのキーワード】

タンパク発現、タンパク発現試薬、タンパク発現装置、タンパク発現サービス、大腸菌、哺乳類、イースト、ピキア属、昆虫、バキュロウイルス、無細胞、コンピテント細胞、タンパク発現量

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