世界の医療産業におけるポリメラーゼ連鎖反応(PCR)市場2014-2020

【英語タイトル】Polymerase Chain Reaction (PCR) In Medical Application - An Analytical Report, 2014-2020

Axis Research Mindが出版した調査資料(DATA70126001)・商品コード:DATA70126001
・発行会社(調査会社):Axis Research Mind
・発行日:2015年12月1日
・ページ数:634
・レポート言語:英語
・レポート形式:PDF
・納品方法:Eメール
・調査対象地域:グローバル
・産業分野:バイオ技術
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【レポートの概要】

Primarily supported by product types; Q-PCR, Assembly PCR, Inverse PCR, RT-PCR and Digital PCR the Polymerase Chain Reaction (PCR) market to witness a value of US$12 billion by 2020. Q-PCR and Digital PCR together account for more than 50% of the global market share.Among the classification of products/tools categories, PCR machines accounts for nearly 29.2% of the overall market share; PCR Reagents stand as the fastest growing market with a CAGR of 10.8% respectively.
Based on PCR application market, Infectious Disease market is generated as fastest growing at a CAGR of 11.2% respectively. PCR Research accounts for 36.8% of the market share by 2017.

Report Focus:
The report “Polymerase Chain Reaction (PCR) In Medical Applications – An Analytical Report, 2014-2020” reviews the latest PCR market trends with a perceptive attempt to disclose the near-future growth prospects. An in-depth analysis on a geographic basis provides strategic business intelligence for life science sector investments. The study reveals profitable investment strategies for pharmaceutical manufacturers, biotechnology companies, laboratories, Contract Research Organizations (CROs) and many more in preferred locations. The report primarily focuses on:
• Emerging market trends
• Advancements in the technological space
• Market demand of the segments (by-region)
• Key growth areas and market size
• Key competitor’s Edge

Estimates are based on online surveys using customized questionnaires by our research team. Besides information from government databases, company websites, press releases & published research reports are also used for estimates.
The analysis primarily deals with three major PCR techniques, product/tools and end-users application market. Further, the subdivided categories include:
PCR Techniques
• Q-PCR
• Reverse-Transcription PCR (RT-PCR)
• Digital PCR
• Assembly PCR
• Inverse PCR
• Other (Multiplex, Nested, Hot Start and Other)

PCR Product/Tools
• PCR Machines
• PCR Reagents
• PCR Detection Kits/Assays
• PCR Consumables
• Other (Software, Pipetting Robot & etc.,)

PCR End-Users Application
• Research
o DNA Sequencing
o DNA Cloning
o Gene Expression
o Other
• Diagnosis
o Cancer
o Tissue Typing
o Genetic Abnormalities
o Other
• Infectious Diseases
• Forensic Sciences &
• Other

The period considered for the PCR market analysis is 2014-2020. The region wise distribution of the market consists of North America (USA and Canada), Europe (Germany, France, United Kingdom, Italy, Spain and Rest of Europe), Asia- Pacific (Japan, China, India, South Korea and Rest of Asia-Pacific), Latin America (Brazil, Columbia, Argentina and Rest of Latin America) and Rest of the World. The market growth rate in the major economies such as the U.S., Japan, China etc. are estimated individually for the upcoming years.
More than 435 leading market players are identified and 45 key companies that project improved market activities in the near future are profiled. The report consists of 371 data charts describing the market shares, sales forecasts and growth prospects. Moreover, key strategic activities in the market including mergers/acquisitions, collaborations/partnerships, product launches/developments are discussed.

【レポートの目次】

I. REPORT FOCUS

PCR TECHNIQUE’S
PRODUCT/TOOLS IN PCR
PCR APPLICATION

A. INTRODUCTION
DEFINING POLYMERASE CHAIN REACTION
POLYMERASE CHAIN REACTION-EXAMINATION
ALL ABOUT PCR ANALYSIS

SCOPE OF POLYMERASE CHAIN REACTION

HISTORY OF POLYMERASE CHAIN REACTION
ALL ABOUT PCR
SPECIMEN PREPARATION
1. ISOLATING THE TARGET DNA – DENATURATION
2. BINDING PRIMERS TO THE DNA CHAIN – ANNEALING
3. MAKING A REPLICA – EXTENSION
PCR

VARIATIONS OF POLYMERASE CHAIN REACTION
BASIC PCR TECHNIQUE’S FLUCTUATIONS
ALLELE-PRECISE PCR
PCA (POLYMERASE CYCLING ASSEMBLY) OR ASSEMBLY PCR
ASYMMETRIC PCR
HELICASE-RELIANT AMPLIFICATION
HOT–START PCR
INTERSEQUENCE-SPECIFIC PCR
REVERSE PCR
LIGATION MEDIATED PCR
METHYLATION SPECIFIC PCR
MINIPRIMER PCR
MULTIPLEX LIGATION-RELIANT PROBE AMPLIFICATION
MULTIPLEX PCR
NESTED PCR
OVERLAP-EXTENSION PCR
QUANTITATIVE PCR
RT-PCR
SOLID-PHASE PCR
TAIL-PCR
TOUCHDOWN PCR
PAN-AC
UNIVERSAL FAST WALKING

MERITS & DEMERITS OF POLYMERASE CHAIN REACTION
STRENGTHS
WEAKNESSES

OPTIMIZING POLYMERASE CHAIN REACTION

THERMAL CYCLERS (POLYMERASE CHAIN REACTION)
1. PCR PRODUCTS BY KEY PLAYERS

PHASES OF POLYMERASE CHAIN REACTION

PARAMETERS FOR SUCCESSFUL PCR
I) METAL ION COFACTORS AND PCR
II) SUBSTRATES AND SUBSTRATE ANALOGS FOR PCR
III) BUFFERS AND SALTS FOR PCR
IV) COSOLVENTS

THERMAL CYCLING CONSIDERATIONS
I) PCR VESSELS
II) TEMPERATURE AND CYCLE TIME OPTIMIZATION
III) PCR AMPLIFICATION CYCLE NUMBER
IV) ENZYME / TARGET
V) HOT START CONDITIONS

THEORY AND METHODOLOGY OF POLYMERASE CHAIN REACTION
METHODOLOGY OF USE

PCR – IMPROVISED TECHNIQUE FOR TESTING NUCLEIC ACIDS
FORMATTING STEP
DENATURATION STEP
ANNEALING STEP
EXTENSION/ELONGATION STEP

FINAL ELONGATION

POLYMERASE CHAIN REACTION IN CLINICAL DETECTIONS

B. TECHNIQUES OF POLYMERASE CHAIN REACTION (PCR)
QUANTITATIVE PCR (Q-PCR) OR REAL-TIME PCR
ADVANTAGES OF REAL-TIME PCR
HISTORY OF REAL-TIME PCR

REVERSE-TRANSCRIPTION (RT) PCR

DIGITAL PCR
DPCR WORKING PRINCIPLE
EXPANSION
MIQE
DIGITAL PCR-PROCEDURE
PRESENTATION OF FUTURE FIXED MICROWELL INTERFACE FOR DIGITAL PCR
NUMERICAL FINDING OF CANCER BIOMARKERS IN PICOLITER DROPLETS
DIGITAL PCR OR ANSWER TO NEW CHALLENGES
THE APPEARANCE OF DIGITAL PCR

2. REAL-TIME PCR V/S TRADITIONAL PCR V/S DIGITAL PCR AT A GLANCE
ASSEMBLY PCR
ASSEMBLY PCR OLIGO MAKER

INVERSE PCR

OTHER
MULTIPLEX PCR
NESTED PCR
HOT–START PCR

POLYMERASE CHAIN REACTION (PCR) – TECHNIQUE’S – GEOGRAPHY MARKET BRIEFING
NORTH AMERICA
EUROPE
ASIA-PACIFIC
LATIN AMERICA
REST OF WORLD

C. PRODUCT/TOOLS IN POLYMERASE CHAIN REACTION (PCR)
PCR MACHINES

REAL-TIME PCR MACHINES

REAL-TIME PCR INSTRUMENTATION
THE PCR SYSTEM

PCR REAGENTS
ROLE OF PCR REAGENTS
GOTAQ® PCR MIX
PRIMERS
PCR REAGENTS
NEXT GENERATION PCR REAGENTS FOR CLINICAL DIAGNOSTICS
PCR REAGENT MARKET TRENDS

DNA TEMPLATE

PCR CONSUMABLES

OTHER
PCR SOFTWARE

PCR ROBOTICS
THE AUTOMATION AND USAGE OF ROBOTICS IN AMPLIFICATION ASSAYS
PRE-PCR ROBOTIC SYSTEM
THE POST-PCR ROBOTIC SYSTEM
INTEGRATED ROBOTIC SYSTEM FOR HIGH SAMPLE THROUGHPUT WITHIN A DNA DATABASING UNIT

PCR ARRAYS
NEED OF PCR ARRAYS
DOCTRINE OF ASSAY CORROBORATION FOR NUCLEIC ACID DIAGNOSTIC TESTS

ASSAY CORROBORATION – AN INTRODUCTION
1. SELECTING AN ASSAY FITTING ITS INTENDED PURPOSE

CONSIDERATIONS TOWARDS PRIMITIVE ASSAY DEVELOPMENTS
A) CARE AND RESTRAINTS
B) PROTECTIONS FOR AVOIDING FALSE-POSITIVE RESULTS
C) SAFEGUARDS FOR AVOIDING NEGATIVE OUTCOMES.
D) STANDARDS’ PREPARATION

ASSAY CORROBORATION – PART I
1. REAGENTS’ OPTIMIZATION BESIDES STANDARDIZATION AND ASCERTAINING CRUCIAL CHECKING PARAMETERS
2. REPRODUCIBILITY
3. DIAGNOSTIC PARTICULARITY AND SENSITIVITY DETERMINATION

ASSAY CORROBORATION – PART 2
1. ASSAY CONDUCT’S PERFORMANCE DETERMINATION
A) ANIMAL POPULATION’S REFERENCE
I) REFERENCE ANIMALS’ NEGATIVITY
II) REFERENCE ANIMALS’ POSITIVITY
III) OTHER ASSAYS’ DETERMINATION OF STATUS OF REFERENCE ANIMALS
2. ENTRY-LEVEL DETERMINATION

ASSAY CORROBORATION – PART 3
1. STARTING ASSAY REPRODUCIBILITY

ASSAY CORROBORATION – PART 4
1. CURRICULUM ACCOMPLISHMENT
2. OBSERVING ASSAY FUNCTIONING’S VALIDITY
A) EXPLANATION OF ANALYSES’ RESULTS – ISSUES UPSETTING ASSAY VALIDITY
B) MAINTAINING CORROBORATION CRITERIA

POLYMERASE CHAIN REACTION (PCR) – PRODUCT/TOOLS – GEOGRAPHY MARKET BRIEFING
NORTH AMERICA
EUROPE
ASIA-PACIFIC
LATIN AMERICA
REST OF WORLD

D. POLYMERASE CHAIN REACTION (PCR) BASED ON APPLICATION
HUMAN GENOME PROJECT
HUMAN HEALTH

GENOME SEQUENCED IN THE PUBLIC (HGP) AND PRIVATE PROJECTS
CELERA GENOMICS PRIVATE – SECTOR PROJECT

FUNDING FOR HUMAN GENOME PROJECT RESEARCH
GENOMIC DNA ISOLATION
DNA MAGNIFICATION AND QUANTIFICATION

APPLYING PCR TECHNIQUES IN USUAL MOLECULAR DIAGNOSTICS
1) THE DOCTRINE OF PCR
DNA MAGNIFICATION
RNA MAGNIFICATION (ANNULLED PCR TRANSCRIPT)
DETECTING PCR AMPLICON
2. TRADITIONAL PCR
3. CUDDLED PCR
4. CONCURRENT PCR
5. COMPLEX PCR

ADVANCES IN MOLECULAR DIAGNOSIS

PCR IN RESEARCH APPLICATION
DNA SEQUENCING
MAXAM-GILBERT SEQUENCING
CHAIN TERMINATOR SEQUENCE
DYE-TERMINATOR SEQUENCE
INSTRUMENTS USED IN DNA SEQUENCING
LARGE-SCALE SEQUENCING
LATEST TECHNIQUES FOR SEQUENCING
IN-VITRO CLONAL AMPLIFICATION
BRIDGE PCR METHOD
HIGH-THROUGHPUT SEQUENCING
SEQUENCING BY LIGATION
PARALLELIZED SEQUENCING
HYBRIDIZATION

MAJOR LANDMARKS IN DNA SEQUENCING
DNA SEQUENCING BY ENZYMATIC SYNTHESIS – PUBLISHED BY FRED SANGER
DYE-BASED SEQUENCING – PUBLISHED BY RICHARD MATHIES
DNA SEQUENCES OF THE FUTURE
DRAFT SEQUENCE AND FINISHED SEQUENCE

DNA CLONING
PCR AND MOLECULAR CLONING
THE BIOMARKER WITH PCR TECHNOLOGY
NEED OF CUSTOM PCR ARRAYS FOR BIOMARKER DISCOVERY AND VALIDATION

OTHER
GENOTYPING

PCR IN DISEASES’ DIAGNOSIS
APPLICATION AND ACCEPTANCE OF PCR TO DIAGNOSE DISEASES
SCOPE
INTERFERENCE
ELISA PROCEDURES
DNA FINGERMARKINGS VIS-À-VIS BREAST CANCER

DISEASE DIAGNOSIS WITH POLYMERASE CHAIN REACTION (PCR) APPLICATION
CATEGORIZATION
CONVEYANCE
ARRESTING CONVEYANCE
IDENTIFICATION AND MEDICAL AID
DIAGNOSES’ PROCEDURES
MICROBE’S CULTURE
RESEARCH
BIOCHEMICAL ANALYSIS
DIAGNOSING MOLECULES

CANCER
LATE POLYMERASE CHAIN REACTION (PCR) APPLICATION- CANCER DETECTION GENOME
INTRODUCTION
HISTORY & IMPORTANCE
STRATAGEM FOR INITIAL CANCER DISCOVERY
LOGIC BEHIND LATE-PCR RESULTANT TESTS
CONCLUSION

GENETIC ABNORMALITIES
PCR IN GENETIC ABNORMALITIES
GENETIC DIAGNOSIS BY USING POLYMERASE CHAIN REACTION (PCR)

TISSUE TYPING

OTHER
PRE-IMPLANTATION GENETIC DIAGNOSIS

INFECTIOUS DISEASE
HIV
TUBERCULOSIS
TESTS

POLYMERASE CHAIN REACTION (PCR) IN FORENSIC SCIENCE
CONDUCTING PCR ANALYSIS
SCRUTINY OF THE PCR PRODUCT
QUANTITATIVE PCR
SYNOPSIS AND FUTURE VISION

DNA TYPING

DNA PROFILING
THE PROCESS OF DNA PROFILING
PCR ANALYSIS
RFLP ANALYSIS
STR ANALYSIS

DNA FINGERPRINT
DISTINCTIVE CHARACTERISTICS OF DNA FINGER PRINT
DNA STRUCTURE
DNA FINGER PRINTING PROCEDURE
(A) SEGREGATION OF DNA
(B) CUTTING, SEPARATING AND SIZING
(C) SHIFTING TO A NYLON SHEET
(D) PROBE
(E) DNA FINGERPRINT
DNA FINGERPRINTS USES
INVESTIGATION AND EVIDENCE COLLECTION
IDENTIFICATION OF PATERNITY
DIAGNOSIS AND CURE FOR DIFFERENT GENETIC DISORDERS
IDENTIFICATION OF THE INDIVIDUAL

FORENSIC MEDICINE
ROLE OF MOLECULAR DIAGNOSTICS IN FORENSIC SCIENCES
AUTOMATED MOLECULAR DIAGNOSTICS
PCR MAGNIFICATION AND FINGERMARKING
THE PAST OF FORENSIC SCIENCE
BRANCHES OF FORENSIC SCIENCE
REFUTABLE FORENSIC TECHNIQUES
LAWSUIT SCIENCE
FORENSIC SCIENCE IN FABLES
PCR TECHNOLOGY METHOD TO FORENSIC SCIENCE
DO-IT-YOURSELF KIT VERSUS KIT TECHNOLOGY
LABORATORY PARAMETERS AND PRECAUTIONS
MERITS OF PCR ENGINEERING
DEMERITS OF PCR ENGINEERING
PCR ENGINEERING’S COST CONSIDERATIONS

OTHER APPLICATION
PRIMITIVE DNA AND DEVELOPMENTAL ASSOCIATIONS
PALEONTOLOGISTS
PCR IN FOOD MICROBIOLOGY
GENETICALLY MODIFIED ORGANISM (GMO) DETECTION
CONTEMPORARY SYSTEMS, BIOLOGICAL STUDIES AND ANIMALS’ CONDUCTS

FUTURE OF POLYMERASE CHAIN REACTION (PCR)

HOME BREW
IN-HOUSE (HOME-BREW) PCR METHODS
HOME-BREW ASSAYS, INCLUDING REAL-TIME PCR

POLYMERASE CHAIN REACTION (PCR) – END-USERS APPLICATION – GEOGRAPHY MARKET BRIEFING
NORTH AMERICA
EUROPE
ASIA-PACIFIC
LATIN AMERICA
REST OF WORLD

PCR – BY END-USERS APPLICATION – RESEARCH APPLICATION
NORTH AMERICA
EUROPE
ASIA-PACIFIC
LATIN AMERICA
REST OF WORLD

PCR – BY END-USERS APPLICATION – DIAGNOSIS APPLICATION
NORTH AMERICA
EUROPE
ASIA-PACIFIC
LATIN AMERICA
REST OF WORLD

II. MARKET ANALYSIS
POLYMERASE CHAIN REACTION (PCR) IN MEDICAL APPLICATION – INDUSTRY SNAPSHOT

A. POLYMERASE CHAIN REACTION (PCR) IN MEDICAL APPLICATION – SEGMENTATION
POLYMERASE CHAIN REACTION (PCR) – GLOBAL

POLYMERASE CHAIN REACTION (PCR) – BY GEOGRAPHY
NORTH AMERICA
EUROPE
ASIA-PACIFIC
LATIN AMERICA
REST OF WORLD

POLYMERASE CHAIN REACTION – BY TECHNIQUE
POLYMERASE CHAIN REACTION (PCR) – TECHNIQUE – BY GEOGRAPHY
Q-PCR
NORTH AMERICA
EUROPE
ASIA-PACIFIC
LATIN AMERICA
REST OF WORLD

REVERSE-TRANSCRIPTION (RT) PCR
NORTH AMERICA
EUROPE
ASIA-PACIFIC
LATIN AMERICA
REST OF WORLD

DIGITAL PCR
NORTH AMERICA
EUROPE
ASIA-PACIFIC
LATIN AMERICA
REST OF WORLD

ASSEMBLY PCR
NORTH AMERICA
EUROPE
ASIA-PACIFIC
LATIN AMERICA
REST OF WORLD

INVERSE PCR
NORTH AMERICA
EUROPE
ASIA-PACIFIC
LATIN AMERICA
REST OF WORLD

OTHER PCR TECHNIQUE
NORTH AMERICA
EUROPE
ASIA-PACIFIC
LATIN AMERICA
REST OF WORLD

POLYMERASE CHAIN REACTION (PCR) – BY PRODUCT/TOOLS
POLYMERASE CHAIN REACTION (PCR) – PRODUCT/TOOLS – GEOGRAPHY
PCR MACHINES
NORTH AMERICA
EUROPE
ASIA-PACIFIC
LATIN AMERICA
REST OF WORLD

PCR REAGENTS
NORTH AMERICA
EUROPE
ASIA-PACIFIC
LATIN AMERICA
REST OF WORLD

PCR DETECTION KITS/ASSAYS
NORTH AMERICA
EUROPE
ASIA-PACIFIC
LATIN AMERICA
REST OF WORLD

PCR CONSUMABLES
NORTH AMERICA
EUROPE
ASIA-PACIFIC
LATIN AMERICA
REST OF WORLD

OTHER PCR PRODUCT/TOOLS
NORTH AMERICA
EUROPE
ASIA-PACIFIC
LATIN AMERICA
REST OF WORLD

POLYMERASE CHAIN REACTION (PCR) – APPLICATION – GLOBAL
POLYMERASE CHAIN REACTION (PCR) – APPLICATION – BY GEOGRAPHY
PCR RESEARCH
NORTH AMERICA
EUROPE
ASIA-PACIFIC
LATIN AMERICA
REST OF WORLD

POLYMERASE CHAIN REACTION (PCR) – APPLICATION – RESEARCH – BY TYPE
POLYMERASE CHAIN REACTION (PCR) – APPLICATION – RESEARCH – BY TYPE- GEOGRAPHY
DNA SEQUENCING
NORTH AMERICA
EUROPE
ASIA-PACIFIC
LATIN AMERICA
REST OF WORLD

DNA CLONING
NORTH AMERICA
EUROPE
ASIA-PACIFIC
LATIN AMERICA
REST OF WORLD

GENE EXPRESSION
NORTH AMERICA
EUROPE
ASIA-PACIFIC
LATIN AMERICA
REST OF WORLD

OTHER RESEARCH APPLICATION
NORTH AMERICA
EUROPE
ASIA-PACIFIC
LATIN AMERICA
REST OF WORLD

PCR DIAGNOSIS
NORTH AMERICA
EUROPE
ASIA-PACIFIC
LATIN AMERICA
REST OF WORLD

POLYMERASE CHAIN REACTION (PCR) – APPLICATION – DIAGNOSIS – BY TYPE
POLYMERASE CHAIN REACTION (PCR) – APPLICATION – DIAGNOSIS – BY TYPE – GEOGRAPHY
CANCER
NORTH AMERICA
EUROPE
ASIA-PACIFIC
LATIN AMERICA
REST OF WORLD

GENETIC ABNORMALITIES
NORTH AMERICA
EUROPE
ASIA-PACIFIC
LATIN AMERICA
REST OF WORLD

TISSUE TYPING
NORTH AMERICA
EUROPE
ASIA-PACIFIC
LATIN AMERICA
REST OF WORLD

OTHER DIAGNOSIS APPLICATION
NORTH AMERICA
EUROPE
ASIA-PACIFIC
LATIN AMERICA
REST OF WORLD

PCR – INFECTIOUS DISEASES
NORTH AMERICA
EUROPE
ASIA-PACIFIC
LATIN AMERICA
REST OF WORLD

PCR – FORENSIC SCIENCES
NORTH AMERICA
EUROPE
ASIA-PACIFIC
LATIN AMERICA
REST OF WORLD

PCR OTHER APPLICATION
NORTH AMERICA
EUROPE
ASIA-PACIFIC
LATIN AMERICA
REST OF WORLD

B. GROWTH RATE ANALYSIS
GLOBAL POLYMERASE CHAIN REACTION (PCR) – MARKET GROWTH RATES

POLYMERASE CHAIN REACTION (PCR) MARKET – TECHNIQUE
GLOBAL PCR TECHNIQUE – GROWTH RATES

Q-PCR
MARKET GROWTH RATES FOR PCR TECHNIQUE – Q-PCR

REVERSE-TRANSCRIPTION PCR (RT-PCR)
MARKET GROWTH RATES FOR PCR TECHNIQUE – REVERSE-TRANSCRIPTION PCR (RT-PCR)

DIGITAL PCR
MARKET GROWTH RATES FOR PCR TECHNIQUE – DIGITAL PCR

ASSEMBLY PCR
MARKET GROWTH RATES FOR PCR TECHNIQUE – ASSEMBLY PCR

INVERSE PCR
MARKET GROWTH RATES FOR PCR TECHNIQUE – INVERSE PCR

POLYMERASE CHAIN REACTION (PCR) MARKET – PRODUCTS/TOOLS
GLOBAL PCR PRODUCTS/TOOLS – GROWTH RATES

PCR MACHINES
MARKET GROWTH RATES FOR PCR PRODUCTS/TOOLS – PCR MACHINES

PCR REAGENTS
MARKET GROWTH RATES FOR PCR PRODUCTS/TOOLS – PCR REAGENTS

PCR DETECTION KITS/ASSAYS
MARKET GROWTH RATES FOR PCR PRODUCTS/TOOLS – PCR DETECTION KITS/ASSAYS

PCR CONSUMABLES
MARKET GROWTH RATES FOR PCR PRODUCTS/TOOLS – PCR CONSUMABLES

POLYMERASE CHAIN REACTION (PCR) MARKET – END-USER APPLICATION
GLOBAL PCR END-USER APPLICATION – GROWTH RATES

PCR RESEARCH
MARKET GROWTH RATES FOR PCR END-USER APPLICATION – PCR RESEARCH

POLYMERASE CHAIN REACTION (PCR) MARKET – RESEARCH – APPLICATION
GLOBAL PCR RESEARCH APPLICATION – GROWTH RATES

DNA SEQUENCING
MARKET GROWTH RATES FOR PCR RESEARCH APPLICATION – DNA SEQUENCING

DNA CLONING
MARKET GROWTH RATES FOR PCR RESEARCH APPLICATION – DNA CLONING

GENE EXPRESSION
MARKET GROWTH RATES FOR PCR RESEARCH APPLICATION – GENE EXPRESSION

PCR DIAGNOSIS
MARKET GROWTH RATES FOR PCR END-USER APPLICATION – PCR DIAGNOSIS

POLYMERASE CHAIN REACTION (PCR) MARKET – DIAGNOSIS – APPLICATION
GLOBAL PCR DIAGNOSIS APPLICATION – GROWTH RATES

CANCER
MARKET GROWTH RATES FOR PCR DIAGNOSIS APPLICATION – CANCER

TISSUE TYPING
MARKET GROWTH RATES FOR PCR DIAGNOSIS APPLICATION – TISSUE TYPING

GENETIC ABNORMALITIES
MARKET GROWTH RATES FOR PCR DIAGNOSIS APPLICATION – GENETIC ABNORMALITIES

INFECTIOUS DISEASES
MARKET GROWTH RATES FOR PCR END-USER APPLICATION – INFECTIOUS DISEASES

FORENSIC SCIENCES
MARKET GROWTH RATES FOR PCR END-USER APPLICATION – FORENSIC SCIENCES

C. INVESTMENT FOCUS
III. INDUSTRY OVERVIEW
A. INDUSTRY ACTIVITIES
MERGERS/ACQUISITIONS/AGREEMENTS/PATENTS GRANTS/JOINT VENTURES/ INNOVATIONS/PRODUCT LAUNCHES/ETC……
COMPLETE GENOMICS ANNOUNCES UK EPILEPSY SOCIETY’S ACQUISITION OF ITS REVOLOCITY™ SUPERSEQUENCER
NEW 384-WELL ASSAY FROM AFFYMETRIX DELIVERS HIGH-THROUGHPUT, PCR-FREE GENE EXPRESSION ANALYSIS
AGILENT TECHNOLOGIES TO ACQUIRE SEAHORSE BIOSCIENCE, INDUSTRY LEADER IN TOOLS FOR MEASURING CELL METABOLISM
COMPREHENSIVE BIOMARKER CENTER NAMED AGILENT TECHNOLOGIES CERTIFIED SERVICE PROVIDER FOR CUSTOM MICRORNA ARRAY SERVICES
ILLUMINA COMPLETES ACQUISITION OF GENOLOGICS
ROCHE TO ACQUIRE KAPA BIOSYSTEMS TO STRENGTHEN NEXT-GENERATION SEQUENCING PRODUCT OFFERINGS
BURNING ROCK AND ILLUMINA COLLABORATE ON MOLECULAR DIAGNOSTICS FOR ONCOLOGY
ROCHE TO ACQUIRE KAPA BIOSYSTEMS TO STRENGTHEN NEXT-GENERATION SEQUENCING PRODUCT OFFERINGS
ROCHE’S PERJETA REGIMEN APPROVED IN EUROPE FOR USE BEFORE SURGERY IN EARLY STAGE AGGRESSIVE BREAST CANCER
WORLD’S FIRST “GO-ANYWHERE” MOLECULAR DIAGNOSTIC SYSTEM UNVEILED AT AACC
QIAGEN COMPANION DIAGNOSTIC WINS FDA APPROVAL FOR USE WITH IRESSA
QIAGEN EXPANDS QIASYMPHONY TEST MENU IN PARTNERSHIP WITH SEEGENE
HITACHI HIGH-TECHNOLOGIES AND QIAGEN ENTER INTO LONG-TERM STRATEGIC COLLABORATION FOR MOLECULAR TESTING
EUROFINS STRENGTHENS ITS FOOTPRINT IN SPECIALTY CLINICAL DIAGNOSTICS WITH THE ACQUISITION OF DIATHERIX LABORATORIES, INC. IN THE US
PERKINELMER LAUNCHES FIRST FULLY AUTOMATED GENETIC DISORDER SCREENING SYSTEM IN CHINA
ABBOTT’S PIONEERING, INFECTIOUS DISEASE TESTING PLATFORM, IRIDICA, NOW AVAILABLE IN EUROPE
ROCHE RECEIVES FDA EMERGENCY USE AUTHORIZATION FOR THE LIGHTMIX EBOLA ZAIRE RRT-PCR TEST
ROCHE UNVEILS MYCOTOOL REAL-TIME PCR KIT VALIDATION REPORT FOR IMPROVED QUALITY CONTROL OF BIOPHARMACEUTICAL PRODUCTS
ROCHE LAUNCHES PCR MOLECULAR DIAGNOSTIC SYSTEM FOR POINT OF CARE ENVIRONMENT
ROCHE DIAGNOSTICS PURCHASES TISSUE DISSECTION TECHNOLOGY FROM AVANSCI BIO
BECKMAN COULTER DIAGNOSTICS AND SEEGENE ANNOUNCE SUPPLY AGREEMENT FOR MULTIPLEX REAGENTS FOR VERIS MOLECULAR DIAGNOSTICS SYSTEM
AFFYMETRIX LAUNCHES SOLUTION TO ENABLE CANCER RESEARCHERS TO RAPIDLY MAP THE FUNCTIONAL IMPACT OF DNA ALTERATIONS ON GENE EXPRESSION PROFILES TO IDENTIFY POTENTIAL CANCER DRIVER EVENTS
AFFYMETRIX EXCLUSIVELY LICENSES TECHNOLOGY FROM PEPTIDE GROOVE LLP FOR HLA TYPING FROM GENOTYPING DATA
AFFYMETRIX AND ARIOSA DIAGNOSTICS ANNOUNCE SIGNING OF MULTI-YEAR SUPPLY AGREEMENT IN SUPPORT OF ARIOSA’S NON-INVASIVE PRENATAL TEST
BIOFIRE DEFENSE, A BIOMÉRIEUX COMPANY, RECEIVES FAST-TRACK AUTHORIZATION OF FILMARRAY® EBOLA TEST
HEALTH CANADA APPROVES FIRST NEAR-PATIENT DNA TEST FOR PERSONALIZED MEDICINE
AGILENT TECHNOLOGIES INTRODUCES MIRNA MICROARRAYS FEATURING LATEST MIRBASE 21 CONTENT
MOBIDIAG ANNOUNCES CE-IVD MARKING OF AMPLIDIAG™ BACTERIAL GE FOR FAST AND ACCURATE PCR-BASED DIAGNOSTICS OF GASTROENTERITIS TEST OPTIMIZES SCREENING OF GASTROENTERITIS-CAUSING BACTERIA DIRECTLY FROM STOOL SAMPLES
NEW ABBOTT TECHNOLOGY MAY UNCOVER THE ROOT OF CRITICAL INFECTIONS AND CUT HEALTH CARE COSTS
AGILENT TECHNOLOGIES INTRODUCES MODULAR REAL-TIME PCR SYSTEM WITH PRECISION OPTICS AND DEPENDABLE THERMAL UNIFORMITY
AGILENT TECHNOLOGIES INTRODUCES NEXT-GENERATION SEQUENCING CANCER RESEARCH PANELS
DAKO LAUNCHES FAST HER2 ISH ASSAY FOR NEW AUTOMATED STAINING PLATFORM IN EUROPE
BIONEER DEVELOPS AN EBOLA VIRUS DETECTION KIT
PERKINELMER LAUNCHES LABCHIP® GX TOUCH AND GXII TOUCHTM AUTOMATED GEL ELECTROPHORESIS SYSTEMS
ALERE RECEIVES FDA CLEARANCE FOR ALERE™ I INFLUENZA A AND B TEST
SALMONELLA SPECIES PCR ASSAY OFFERS VALIDATED METHOD FOR FAST, SIMPLE DETECTION OF FOOD PATHOGENS
BIO-RAD ACQUIRES GNUBIO AND DNA SEQUENCING TECHNOLOGY
OGT TO LAUNCH CANCER SEQUENCING PANEL AT ACGS
OGT EXPANDS GENOMIC MEDICINE PORTFOLIO WITH ACQUISITION OF CYTOCELL
ASPER BIOTECH LAUNCHES MALE FACTOR INFERTILITY TEST
AUTOMATED TRUSEQ® STRANDED TOTAL RNA LIBRARY PREPARATION METHOD FOR EPPENDORF EPMOTION
NOVOGENE ACQUIRES AN ILLUMINA HISEQ X TEN SEQUENCING SYSTEM
BIOMÉRIEUX FINALIZES ACQUISITION OF THE U.S. COMPANY BIOFIRE, SPECIALIZED IN MOLECULAR BIOLOGY
AFFYMETRIX RECEIVES FDA CLEARANCE OF FIRST-OF-ITS-KIND POSTNATAL TEST FOR DEVELOPMENTAL DELAYS AND INTELLECTUAL DISABILITIES IN CHILDREN
EPPENDORF LAUNCHES THE NEW TRANSFERMAN® 4R MICROMANIPULATOR WITH UNPRECEDENTED MOVEMENT CONTROL
TAKARA BIO LAUNCHES NEW RESEARCH REAGENTS RELATING TO THE ADENO-ASSOCIATED VIRUS VECTOR FOR GENE TRANSDUCTION
NEW MICROARRAY FOR IDENTIFYING AND SUBTYPING PATHOGENIC E. COLI USING UNIQUE DNA SIGNATURES
AFFYMETRIX LAUNCHES NEW ONCOSCAN™ FFPE ASSAY KIT
AFFYMETRIX INTRODUCES NEW AXIOM® 384HT GENOTYPING FORMAT ENABLING NEW LEVEL OF COST-EFFECTIVE, HIGH-THROUGHPUT GENOTYPING STUDIES
AFFYMETRIX AND BIODISCOVERY ANNOUNCE SOFTWARE FOR ANALYSIS OF WHOLE GENOME COPY NUMBER DATA GENERATED FROM FFPE SOLID TUMOR SAMPLES FOR ACCELERATING CANCER TRANSLATIONAL RESEARCH
COST-EFFECTIVE MULTIPLEX PCR KIT FOR DISTINGUISHING HORSE AND BEEF!
THERMO FISHER SCIENTIFIC TO ACQUIRE LIFE TECHNOLOGIES CORPORATION
VEREDUS LABORATORIES APPROVES THE CURRENT VERSION OF VEREFLU™
BGI-SHENZHEN ACQUIRES COMPLETE GENOMICS INC.
INIBSA GROUP ACQUIRES BIOTECH BIOTOOLS.
AFFYMETRIX AND DNA LINK SIGN PARTNERSHIP FOR PBA PROGRAM FOR HUMAN IDENTIFICATION
MAST UNVEILS NEW ISOTHERMAL NUCLEIC ACID AMPLIFICATION KITS.
FULL SERVICE OF MICROBIAL DIVERSITY PROFILING IS NOW AVAILABLE.
BIOSEARCH TECHNOLOGIES ANNOUNCES ACQUISITION OF DIVISIONS OF DNA TECHNOLOGY AND VITRABIO.
COUNT YOUR DNA WITH DIGITAL PCR AT TATAA BIOCENTER.
MOBIDIAG’S PROVE-IT™ BONE & JOINT, A HIGH-QUALITY MULTIPLEXED MOLECULAR DIAGNOSTIC TECHNOLOGY FOR INFECTIOUS DISEASES, ACHIEVES CE-IVD MARKING.
SPOTSTUDIO™‘S EARLY ACCESS PROGRAM STARTED.
FULL PD+ SEQUENCING SERVICE IN TUBE FORMATS IS NOW AVAILABLE.
THERMO FISHER SCIENTIFIC LAUNCHES SURETECT PCR SYSTEM FOR FOOD PATHOGEN DETECTION
CELL SIGNALING TECHNOLOGY RECEIVES PATENT FOR PCR METHODS FOR DETECTION OF A SUBSET OF TREATABLE NON-SMALL CELL LUNG CANCERS
BIO-RAD ACQUIRES ABD SEROTEC
THERMO FISHER SCIENTIFIC SHOWCASES INTEGRATED LAB AUTOMATION PORTFOLIO AT SLAS 2013
ILLUMINA ROLLS OUT SEQUENCING TECHNOLOGY INNOVATIONS
TATAA BIOCENTER INTRODUCES QPCR WORKFLOW

B. MARKET TRENDS
SPARTAN BIOSCIENCE DX-12™ DNA ANALYZER – A BOON TO BIOTECHNOLOGY
REDDYMIX – A BUFFER FOR PCR REAGENTS
NEXT GENERATION PCR APPROVES EVOLUTION POLYMERASES
QUICKPROBE(TM) QPCR- A BONUS TO LIFE SCIENCES COMPANIES
MASTER CLEAR CAP STRIPS® – AN ADDITION TO PCR CONSUMABLES
DIGITAL PCR TECHNOLOGY BY FLUIDIGM
GREENECHIP TECHNOLOGY- UNPREJUDICED PATHOGEN DISCOVERY
INCREASING DEMAND FOR QRT-PCR PRODUCTS
QIAGEN’S NEW SOLUTION TO ACCELERATE PCR
OPTO TECHNOLOGY’S NEW INVENTION – OTHP-0050
TIE UP BETWEEN FISHER BIOSCIENCES AND APPLIED BIOSYSTEMS
FISHER BIOSCIENCES AND DYOMICS MERGE FOR BETTERMENT
PCR MACHINES – IMPACT ON LIFE SCIENCES EQUIPMENT.
A HOME-BREW REAL-TIME PCR ASSAY FOR CONSISTENT RECOGNITION AND MEASUREMENT OF MATURE MIR-122
RELEVANCE OF THE POLYMERASE CHAIN REACTION TO QUICK EXAMINATION OF BREWERY YEAST STRAINS
AMPLIFICATION INVENTORY: DPCR OR QPCR?
DESCRIPTION OF QPCR AND DPCR
THE GOLD STANDARD
WHAT NEEDS TO BE ACCOMPLISHED?

C. INDUSTRY LEADERS
ABBOTT LABORATORIES (USA)
AGILENT TECHNOLOGIES INC (USA)
BIONEER INC (USA)
COMPLETE GENOMICS, INC. (USA)
EPICENTRE® BIOTECHNOLOGIES (USA)
GENISPHERE INC. (USA)
MAXIM BIOTECH, INC (USA)
OCIMUM BIOSOLUTIONS LTD.
QIAGEN INC (USA)
SACACE BIOTECHNOLOGIES S.R.L. (ITALY)
TAKARA BIO, INC.
THERMO FISHER SCIENTIFIC, INC.
LIGHTUP TECHNOLOGIES AB (SWEDEN)
HY LABORATORIES LTD (ISRAEL)
D. POLYMERASE CHAIN REACTION (PCR) IN MEDICAL APPLICATION – A LOOK A HEAD..!!

E. KEY COMPANY PROFILES

F. POLYMERASE CHAIN REACTION (PCR) – PATENTS
PCR PATENT EXPIRY AND ITS EFFECT ON MARKET STRATEGIES
EXPIRY OF PCR PATENT OFFERS EXCITING GROWTH OPPORTUNITIES FOR NUCLEIC ACID PURIFICATION AND AMPLIFICATION TECHNOLOGIES
INNOVATIVE FEATURES WIDEN APPLICATION BASE AND BOOST REVENUE

PATENT EXPIRATION
MOLECULAR DIAGNOSTICS UNCHAINED
THE POLYMERASE CHAIN REACTION PATENT ENDING: AN EXPIRING PATENT MARKS THE END OF A BIOTECHNOLOGICAL ERA
EXPIRING PATENTS, UPTICK IN BIOTECH SPENDING COULD SPUR QPCR-BASED DX, TOOL DEVELOPMENT
THE POLYMERASE CHAIN REACTION PATENTS: GOING, GOING,… STILL GOING
THE POST-PATENT OPPORTUNITY
PATENT WARS
PCR – A PATENT THAT REVOLUTIONIZED BIOTECHNOLOGY AND LAUNCHED A TV SERIES
PATENT RULING COULD CUT PCR ENZYME PRICES
PCR PATENT ISSUES
1. INTRODUCTION
2. INTELLECTUAL PROPERTY RIGHTS
3. NAVIGATING THE PCR PATENT MINEFIELD
3.1. OBTAINING RIGHTS TO PRACTICE PCR
3.2. BONA-FIDE RESEARCHERS ARE NOT INFRINGERS
3.3. NOT EVERY PATENT IS A VALID PATENT

IV. INDUSTRY COMPANY DATABASE

V. APPENDIX
A. RESEARCH FOCUS
B. ABOUT AXIS RESEARCH MIND
C. DISCLAIMER
D. FEEDBACK



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