リキッドバイオプシー研究ツール・サービス・診断の世界市場

【英語タイトル】Liquid Biopsy Research Tools, Services and Diagnostics: Global Markets

BCC Researchが出版した調査資料(BCC21AP009)・商品コード:BCC21AP009
・発行会社(調査会社):BCC Research
・発行日:2021年3月
・ページ数:345
・レポート言語:英語
・レポート形式:PDF
・納品方法:Eメール(受注後2営業日)
・調査対象地域:グローバル
・産業分野:医療
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❖ レポートの概要 ❖

本調査レポートでは、リキッドバイオプシー研究ツール・サービス・診断の世界市場を調査・分析し、イントロダクション、サマリー・ハイライト、市場概要、技術背景、リキッドバイオプシーイニシアチブ、産業別(シーケンシング機器、第三世代シーケンシング、シーケンシングインフォマティクス、PCR、液滴デジタルPCR、その他)分析、買収/戦略的提携、リキッドバイオプシー市場、特許レビュー/新開発、企業情報などを掲載しています。
・イントロダクション
・サマリー・ハイライト
・市場概要
・技術背景
・リキッドバイオプシーイニシアチブ
・リキッドバイオプシー研究ツール・サービス・診断の世界市場規模:用途別(癌、精密医療、バイオマーカー、リプロダクティブヘルス、移植診断)
・リキッドバイオプシー研究ツール・サービス・診断の世界市場規模:産業別(シーケンシング機器、第三世代シーケンシング、シーケンシングインフォマティクス、PCR、液滴デジタルPCR、その他)
・買収/戦略的提携
・リキッドバイオプシー市場
・特許レビュー/新開発
・企業情報

The scope of the report includes liquid biopsy technologies, applications, industry subsegments, biomarker technologies, major funding initiatives, patents and companies. The market sizes for liquid biopsy diagnostics are given for 2019, 2020 and 2025 (forecasted).

This report reviews liquid biopsy biomarkers and technologies and provides background on why liquid biopsy is increasingly viewed as a replacement for, or a companion to, tissue biopsy.The report then discusses several of the significant large-scale research initiatives that are contributing to liquid biopsy development.

The key forces driving the market are enumerated.

The structures of several important industry subsectors, as well as major industry acquisitions and strategic alliances from January 2019 through January 2021, are reviewed. The industry subsectors that have been analyzed include DNA sequencing and instruments; long-read sequencing; sequencing informatics; PCR; droplet digital PCR; CTC capture and detection; liquid biopsy; cancer screening/early detection; and noninvasive prenatal screening.

The market for liquid biopsy diagnostics is analyzed in depth. The market is analyzed by -
- Application (cancer, reproductive health, transplant);
- Biomarker type, including circulating nucleic acids, circulating tumor cells, and other (extracellular vesicles, proteins);
- Analysis platforms including NGS, PCR and other (microarray, Sanger sequencing, immunoassay, immunocytochemistry, and cell capture);
- Analysis purpose (screening/early detection, diagnosis, therapy guidance, monitoring); and
- Geography (North America, Europe, Asia-Pacific, Rest of World).
- Market data covers 2019, 2020 and 2025 (forecasted).

The report contains a large profile compilation of more than 200 companies in the liquid biopsy industry.

The analyst provides a summary of the main industry acquisitions and strategic alliances from January 2019 through January 2021, including key alliance trends.

Report Includes:
- 29 data tables and 56 additional tables
- An overview of the global market for liquid biopsy research tools, services and diagnostics
- Estimation of the market size and analyses of global market trends, with data from 2019 and 2020, and projections of compound annual growth rates (CAGRs) through 2025
- Characterization and quantification of market potential for liquid biopsy diagnostics by application, biomarker type, analysis platform, analysis purpose and geographical region
- Discussion on significant large-scale research initiatives that are contributing to liquid biopsy market development
- Examination of various conventional biopsy methods and information on how liquid biopsy enabling technologies address the issues and are gaining significant traction with key opinion leaders
- Identification of market drivers, restraints and other forces influencing the growth of the liquid biopsy market
- Market share analysis of the key companies of the industry and coverage of events like mergers & acquisitions, joint ventures, collaborations or partnerships, and other key market strategies
- Review of patents and new developments in circulating tumor cell (CTC) technologies, exosome technologies, cell-free DNA technologies, and cancer biomarkers
- Company profiles of major liquid biopsy market players, including Bard1 Life Sciences Ltd., Becton, Dickinson and Co. (BD), Bio-Rad Laboratories Inc., Danaher Corp., Exosome Sciences Inc., Qiagen NV and Roche Holding AG

Summary:
Liquid biopsy represents a very attractive option as a supplement or alternative to doing a tissue biopsy for applications in reproductive health, cancer and transplant medicine.Liquid biopsy involves detecting and analyzing “foreign”-derived biomarkers present in body fluids such as blood or urine.

The origin of the biomarker defines the liquid biopsy application: tumor (cancer applications); fetus (prenatal screening applications); or transplanted organ (transplant medicine applications).

Liquid biopsy is creating a paradigm shift in medicine, and this is opening significant market opportunities. These market segments are particularly promising for the following liquid biopsy applications: noninvasive prenatal screening for average-risk populations; cancer screening and early detection; and recurrence monitoring for cancer patients.

Biomarker types of most interest include cell-free DNA (cfDNA), circulating tumor cells (CTCs) and exosomes. Ongoing advances in sensitive molecular technologies such as next-generation DNA sequencing (NGS) and digital polymerase chain reaction (dPCR) enable the detection of biomarkers that are present in fluids at very low concentrations, creating entry points for early disease detection and for the monitoring of disease recurrence.

When compared with conventional tissue biopsy, liquid biopsy tests address a significant medical need by delivering a biopsy that is noninvasive and has little or no risk of medical complications.The validation of this testing platform and demonstration of clinical utility has been proven in the high-risk pregnancy segment of the NIPT industry, resulting in high market penetration.

This early success is now translating to additional market opportunities in prenatal testing, cancer management and transplant medicine.

❖ レポートの目次 ❖

Chapter 1 Introduction
Study Goals and Objectives
Reasons for Doing This Study
Scope of Report
Information Sources
Methodology
Geographic Breakdown
Analyst’s Credentials

Chapter 2 Summary and Highlights

Chapter 3 Overview
Introduction
Scope of Report
Liquid Biopsy vs. Traditional Biopsy
Markets
Forces Driving Growth
Key Trends
Industry

Chapter 4 Technology Background
Liquid Biopsy Biomarkers
Cancer Genomics
Noninvasive Prenatal Testing (NIPT)
Circulating Tumor Cell Technologies (CTCs)
CTC Workflow
Cell Isolation Technologies
CTC Sample Preparation Technologies
CTC Downstream Analysis Technologies
Comparison of Liquid Biopsy with Conventional Biopsy
Cancer Testing
Prenatal Testing

Chapter 5 Liquid Biopsy Initiatives
Introduction
Liquid Biopsy-Related Research and Development
Initiatives and Programs
Population Sequencing Projects

Chapter 6 Liquid Biopsy Applications
Introduction
Cancer Applications
Precision Medicine
Liquid Biopsy Biomarkers
Cancer Market Segments
Reproductive Health Applications
Transplant Diagnostic Applications

Chapter 7 Liquid Biopsy Industry
Introduction
Sequencing Instruments Industry
Third-Generation Sequencing Industry
Sequencing Informatics Industry
PCR Industry
Droplet Digital PCR Industry
CTC Capture and Detection Industry
Liquid Biopsy Assay Industry
Liquid Biopsy Cancer Screening/Early Detection Industry
Noninvasive Prenatal Testing (NIPT) Industry

Chapter 8 Industry Acquisitions and Strategic Alliances
Acquisitions
Strategic Alliances
Key Trends
Summary of Alliances

Chapter 9 Markets for Liquid Biopsy
Forces Driving Growth in the Markets for Liquid Biopsy
Precision Medicine
Rise of Tissue-Agnostic Drugs
Genomics Initiatives
Clinical Need for Better Diagnostics
Role of Key Stakeholders
Emerging “Mega” Applications
COVID-19 Environment
Rise in the Importance of China
Impact of COVID-19 on the Global Market for Liquid Biopsy
Global Market for Liquid Biopsy by Clinical Category
Global Market for Liquid Biopsy by Purpose of Analysis
Global Market for Liquid Biopsy by Biomarker Type
Global Market for Liquid Biopsy by Analysis Platform
Global Market for Noninvasive Prenatal Testing
Global Market for Liquid Biopsy in Cancer Applications
Global Market for Liquid Biopsy for Cancer Diagnostics by Cancer Site
Global Market for Liquid Biopsy in Cancer Applications by Purpose of Analysis
Global Market for Liquid Biopsy in Cancer Applications by Biomarker Class
Global Market for Liquid Biopsy in Cancer Applications by Analysis Method
Global Market for Liquid Biopsy for Transplant Diagnostics
Global Market for Liquid Biopsy by Geographic Region

Chapter 10 Patent Review/New Developments
Patents on Circulating Tumor Cell (CTC) Technologies
Patents on Exosome Technologies
Patents on Cell-Free DNA Technologies
Biomarker-Related Patents
Patent Considerations for the Use of Artificial Intelligence in Cancer Diagnostics
Lawsuits on Liquid Biopsy Patents

Chapter 11 Company Profiles
4D LIFETEC AG
ACCURAGEN INC.
ACCUROME HEALTH INC.
ADAPTIVE BIOTECHNOLOGIES INC.
ADVANCED CELL DIAGNOSTICS INC.
AGILENT TECHNOLOGIES INC.
AKADEUM LIFE SCIENCES
ALCEDIAG
AMOY DIAGNOSTICS CO., LTD.
ANGLE PLC
APOCELL INC.
APOSTLE INC.
ARCEDI BIOTECH APS
ARCHER DX
ARUP LABORATORIES
ASURAGEN INC.
AVIVA BIOMED INC.
AVIVA BIOSCIENCES
BARD1 LIFE SCIENCES LTD.
BASE GENOMICS
BAYLOR GENETICS
BECTON, DICKINSON AND CO.
BERRY GENOMICS CO., LTD.
BGI SHENZHEN
BIOCARTIS NV
BIOCEPT INC.
BIODESIX INC.
BIOFLUIDICA INC.
BIOGAZELLE
BIOLIDICS LTD.
BIOLOGICAL DYNAMICS INC.
BIOPROGNOS SL
BIO-RAD LABORATORIES INC.
BIO-TECHNE CORP.
BITBIOME INC.
BLUESTAR GENOMICS INC.
BURNING ROCK BIOTECH LTD.
C2I GENOMICS
CADEX GENOMICS CORP.
CAMBRIDGE EPIGENETIX
CANCER GENETICS INC.
CANEXIA HEALTH
CAPIO BIOSCIENCES
CAPTIS DIAGNOSTICS INC.
CAREDX INC.
CARIS LIFE SCIENCE
CEGAT GMBH
CELLMAX LIFE
CELL MICROSYSTEMS INC.
CELSEE DIAGNOSTICS
CELTIC B.V.
CHRONIX BIOMEDICAL
CIRCULOGENE THERANOSTICS
CLARET BIOSCIENCE
CLINICAL GENOMICS TECHNOLOGIES
CODIAK BIOSCIENCES
CRADLE GENOMICS
CYCLOMICS
CYGNUS BIOSCIENCES CO., LTD.
CYTOTRACK APS
DANAHER CORP.
DATAR CANCER GENETICS LTD.
DELFI DIAGNOSTICS
DIACARTA INC.
DIAGNOLOGIX LLC
DIAGNOMICS
DIAMIR BIO
DNALYTICS
DNANEXUS INC.
DOVETAIL GENOMICS LLC
EARLYDX INC.
EDP BIOTECH CORP.
EPIC SCIENCES INC.
EPIGENOMICS AG
EUROFINS SCIENTIFIC
EXACT SCIENCES CORP.
EXOSOME SCIENCES INC.
EXOPERT
EXOSOMICS SPA
EZLIFE BIO INC.
FABRIC GENOMICS
FLUXION BIOSCIENCES INC.
FREENOME INC.
GENAPSYS INC.
GENECAST INC.
GENEDX INC.
GENETRON HEALTH TECHNOLOGIES
GENESEQ BIOSCIENCES PTY LTD.
GENEXOSOME TECHNOLOGIES INC.
GENOMICTREE
GENOMONCOLOGY
GENOSABER
GENOSITY
GRAIL INC.
GUARDANT HEALTH INC.
HTG MOLECULAR DIAGNOSTICS INC.
IDL BIOTECH
ID SOLUTIONS
ILLUMINA INC.
IMMUNOVIA AB
INCELLDX INC.
INEX INNOVATE PTE. LTD.
INIVATA LTD.
INTERPACE BIOSCIENCES INC.
INVITAE INC.
INVIVOSCRIBE INC.
JABREHOO MEDTECH CO., LTD.
JBS SCIENCE INC.
KONINKLIJKE PHILIPS N.V.
LABORATORY CORP. OF AMERICA INC.
LABRINTH BIOTECH INC.
LARIAT BIOSCIENCES INC.
LEXENT BIO INC.
LIQUID BIOPSY LABS
LUCENCE DIAGNOSTICS PTE. LTD.
LUNGLIFE AI INC.
MDNA LIFE SCIENCES INC.
MDXHEALTH INC.
MEDGENOME INC.
MENARINI SILICON BIOSYSTEMS SPA
MERCK KGAA
MICAREO RARE CELL DIAGNOSTICS
MIR SCIENTIFIC
MIRXES
MURSLA LTD
MUTANTDX
MYRIAD GENETICS INC.
NAMOCELL INC.
NANOSTRING TECHNOLOGIES INC.
NANOVIEW BIOSCIENCES INC.
NATERA INC.
NAVERIS INC.
NEOGENOMICS LABORATORIES
NEO NEW ONCOLOGY GMBH
NEW ENGLAND BIOLABS
NEW HORIZON HEALTH LTD.
NIPD GENETICS
NOVIGENIX SA
NOVOGENE CO., LTD.
NRICHDX INC.
NUCLEIX
NUPROBE INC.
NX PRENATAL INC.
ONCIMMUNE HOLDINGS PLC
ONCOCYTE CORP.
ONCODNA S.A.
ONCOLAB DIAGNOSTICS GMBH
OPKO HEALTH
OTRACES INC.
OXFORD NANOPORE TECHNOLOGIES LTD.
PACIFIC BIOSCIENCES OF CALIFORNIA INC.
PANGAEA ONCOLOGY
PERSONAL GENOME DIAGNOSTICS INC.
PERSUASIVE
PFDENA INC.
PHASE SCIENTIFIC
PIERIANDX
PREDICINE INC.
PROVISTA DIAGNOSTICS INC.
QCDX LLC
QIAGEN NV
QUANTAPORE INC.
QUANTGENE INC.
QUANTUM BIOSYSTEMS INC.
QUANTUMDX
QUEST DIAGNOSTICS INC.
RARECELLS SAS
RAVGEN
REAL TIME GENOMICS INC.
RESOLUTION BIOSCIENCE INC.
ROCHE HOLDING AG
SAGA DIAGNOSTICS AB
SANOMICS LTD.
SANO GENETICS
SCREENCELL
SEEKIN
SEER INC.
SERACARE LIFE SCIENCES INC.
SEQUENCING.COM
SEVEN BRIDGES GENOMICS INC.
SINGLE TECHNOLOGIES
SINGLERA GENOMICS INC.
SMARTCACTCH
SOMALOGIC INC.
STAGE ZERO LIFE SCIENCES
STILLA TECHNOLOGIES
STRAND LIFE SCIENCES PVT., LTD.
STRATA ONCOLOGY
STRATOS GENOMICS INC.
SYAPSE
SYSMEX INOSTICS GMBH
TAILAI BIOSCIENCES CO., LTD.
TAKARA BIO INC.
TELEXOS GMBH
THERMO FISHER SCIENTIFIC INC.
TWINSTRAND BIOSCIENCES
TYMORA ANALYTICAL OPERATIONS LLC
UBIQUITY GENOMICS INC.
UNIVERSAL DIAGNOSTICS SL
VELA DIAGNOSTICS
VERACYTE
VOLITIONRX
VORTEX BIOSCIENCES
XING TECHNOLOGIES LLC
YIKON GENOMICS CO., LTD.
YOURGENE HEALTH PLC



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